PlasGUN: gene prediction in plasmid metagenomic short reads using deep learning
PlasGUN: gene prediction in plasmid metagenomic short reads using deep learning
复制标题
PlasGUN：使用深度学习在质粒宏基因组短读中进行基因预测。
DOI：
10.1093/bioinformatics/btaa103
复制
发表时间：
2020-05-15
期刊：
影响因子：
5.8
通讯作者：
Zhu, Huaiqiu
中科院分区：
文献类型：
--
作者：
Fang, Zhencheng;Tan, Jie;Zhu, Huaiqiu
摘要：我们提出了第一个基因预测工具PlasGUN，用于质粒宏基因组短读数据。该工具基于多输入卷积神经网络的深度学习算法开发，在人工短读的基准数据集上测试了更好的性能，并且与主要针对染色体衍生短读设计的传统基因预测工具相比，对真实质粒宏基因组数据提供了更可靠的结果。
aSummary: We present the first tool of gene prediction, PlasGUN, for plasmid metagenomic short-read data. The tool, developed based on deep learning algorithm of multiple input Convolutional Neural Network, demonstrates much better performance when tested on a benchmark dataset of artificial short reads and presents more reliable results for real plasmid metagenomic data than traditional gene prediction tools designed primarily for chromosome-derived short reads.