Subregions of human MT complex revealed by comparative MEG and direct electrocorticographic recordings
Subregions of human MT complex revealed by comparative MEG and direct electrocorticographic recordings
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DOI：
10.1016/j.clinph.2004.03.030
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发表时间：
2004-09-01
影响因子：
4.7
通讯作者：
Shibasaki, H
中科院分区：
文献类型：
--
作者：
Matsumoto, R;Ikeda, A;Shibasaki, H
目的：目的：对1例癫痫手术患者的视觉运动复合波（visual motion complex，MT +）进行定位并研究其反应特性。方法：1例17岁癫痫患者，在右侧颞顶枕区进行硬膜下电极有创监测。MT +皮层电刺激和皮层上视觉诱发电位时间锁定的正弦光栅（运动VEP）的运动开始进行了研究。结果：运动VEP显示MT +内有两个亚区，分别产生早电位和晚电位。早期的活动与峰值约130毫秒定位在一个单一的电极位于紧接尾侧的初始部分的上升支的上级颞沟（AL-STS）。晚期活动，峰值在242-274 ms，位于腹侧-喙侧的三个电极。在具有运动VEP的四个电极中，在最尾侧对的皮层刺激引起涉及整个视野的深度运动知觉。脑磁图（MEG）除了显示回冠上的两个亚区外，还显示AL-STS吻侧的另一个亚区具有迟发运动VEF。结论：结合MEG记录，本侵入性探索显示人类MT +在颞顶枕交界处的一个局灶性区域，并描绘了可能的三个亚区，所示的不同的潜伏期和分布的运动VEP/VEFs。(C)2004年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: To locate the visual motion complex (MT +) and study its response properties in an epilepsy surgery patient.Methods: A 17-year-old epilepsy patient underwent invasive monitoring with subdural electrodes in the right temporo-parieto-occipital area. MT + was investigated by cortical electric stimulation and by epicortical visual evoked potentials time-locked to motion onset of sinusoidal gratings (motion VEP). Motion-related visual evoked magnetic field (motion VEF) was also recorded before the electrode implantation to complement the invasive recording.Results: Motion VEPs revealed two subregions within MT +, generating early and late potentials respectively. The early activity with a peak around 130 ms was localized at a single electrode situated immediately caudal to the initial portion of the ascending limb of the superior temporal sulcus (AL-STS). The late activity, peaking at 242-274 ms, was located ventro-rostrally over three electrodes. Among the four electrodes with motion VEPs, cortical stimulation at the most caudal pair elicited motion-in-depth perception involving the whole visual field. In addition to two subregions revealed on the gyral crown, magnetoencephalography (MEG) demonstrated another subregion with a late motion VEF in AL-STS immediately rostral. to the electrode with the early motion VEP.Conclusions: In combination with MEG recording, the present invasive exploration demonstrated human MT + in a focal area of the temporo-parieto-occipital junction and delineated possible three subregions as indicated by the different latencies and distributions of the motion VEP/VEFs.Significance: Comparative MEG and direct electrocorticographic recordings delineated possible subregions within the human MT complex. (C) 2004 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.