The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana
The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana
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DOI：
10.1038/nature00954
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发表时间：
2002-09-05
期刊：
影响因子：
64.8
通讯作者：
Amasino, RM
中科院分区：
文献类型：
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作者：
Doyle, MR;Davis, SJ;Amasino, RM
许多植物利用日照长度作为环境线索，以确保从营养生长向生殖生长转变的适当时机。日长感知涉及白天和黑夜的相对长度之间的相互作用，以及由植物生物钟控制的内源性节律（1）。因此，昼夜节律调节缺陷的植物无法正确调节开花过渡的时间（2）。在这里，我们描述的基因EARLY FLOWARD 4（ELF 4），这是参与光周期感知和昼夜节律调节。ELF 4促进时钟的准确性，并且在没有每日光/暗周期的情况下需要持续的节奏。elf 4突变体表现出昼夜节律相关1（CCA 1）的表达减弱，该基因被认为是一种中央振荡器成分（3，4）。此外，elf 4植物短暂地表现出输出节律，在成为植物之前具有高度可变的周期长度。elf 4的突变导致在非诱导光周期中提前开花，这可能是由CONSTANS（CO）的量升高引起的，CONSTANS（CO）是一种促进成花诱导的基因（5）。
Many plants use day length as an environmental cue to ensure proper timing of the switch from vegetative to reproductive growth. Day-length sensing involves an interaction between the relative length of day and night, and endogenous rhythms that are controlled by the plant circadian clock(1). Thus, plants with defects in circadian regulation cannot properly regulate the timing of the floral transition(2). Here we describe the gene EARLY FLOWERING 4 (ELF4), which is involved in photoperiod perception and circadian regulation. ELF4 promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles. elf4 mutants show attenuated expression of CIRCADIAN CLOCK ASSOCIATED 1 (CCA1), a gene that is thought to function as a central oscillator component(3,4). In addition, elf4 plants transiently show output rhythms with highly variable period lengths before becoming arrhythmic. Mutations in elf4 result in early flowering in non-inductive photoperiods, which is probably caused by elevated amounts of CONSTANS (CO), a gene that promotes floral induction(5).