HETEROGENOUS DISTRIBUTION OF TYPE-IV COLLAGEN, ENTACTIN, HEPARAN-SULFATE PROTEOGLYCAN, AND LAMININ AMONG RENAL BASEMENT-MEMBRANES AS DEMONSTRATED BY QUANTITATIVE IMMUNOCYTOCHEMISTRY
HETEROGENOUS DISTRIBUTION OF TYPE-IV COLLAGEN, ENTACTIN, HEPARAN-SULFATE PROTEOGLYCAN, AND LAMININ AMONG RENAL BASEMENT-MEMBRANES AS DEMONSTRATED BY QUANTITATIVE IMMUNOCYTOCHEMISTRY
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DOI：
10.1177/37.6.2723404
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发表时间：
1989-06-01
影响因子：
3.2
通讯作者：
BENDAYAN, M
中科院分区：
文献类型：
--
作者：
DESJARDINS, M;BENDAYAN, M
Type IV collagen, entactin, heparan sulfate proteoglycan, and laminin antigenic sites were revealed on various rat renal basement membranes by use of protein A-gold immunocytochemistry. The basement membranes of the proximal and distal convoluted tubules, those of Bowman''s capsule and glomerulus, and the mesangial matrix were labeled for all the antigens but to differing extents. Control experiments confirmed the specificity of these labelings. Quantitative evaluation revealed an important heterogeneity for each antigen among the various basement membranes. This heterogeneity suggests that the basement membrane components must arrange themselves in different ways, possibly to account for differences in functional properties of the various renal structures.
