Location of parotid preganglionic neurons in the inferior salivatory nucleus and their relation to the superior salivatory nucleus of rat
Location of parotid preganglionic neurons in the inferior salivatory nucleus and their relation to the superior salivatory nucleus of rat
复制标题
大鼠腮腺节前神经元在下唾液核的位置及其与上唾液核的关系
DOI：
10.1016/j.neulet.2008.05.099
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发表时间：
2008
影响因子：
2.5
通讯作者：
I. Tóth
中科院分区：
文献类型：
--
作者：
Ödön Rezek;Z. Boldogkői;Dóra Tombácz;Csaba Kővágó;I. Gerendai;M. Palkovits;I. Tóth
在主要的脑图中，大鼠的唾液核的位置被描绘从面神经根的水平到孤立束核的吻尖的水平。大多数已发表的数据涉及上唾核（SSN）。在本研究中，利用逆行跨神经元标记技术测定了通过耳神经节支配腮腺的下涎核（ISN）副交感神经节前神经元的地形。将病毒注射到腮腺后，标记副交感神经细胞、交感神经细胞和感觉神经细胞。大多数ISN神经元位于面部运动核的背侧，嵌入细胞网状结构中。除了ISN神经元外，病毒标记的细胞还存在于胸脊髓的中外侧（IML）细胞柱、脑干儿茶酚胺组和髓质中缝神经元中。在腮腺注射病毒前切除同侧颈上神经节不影响ISN神经元的标记，但在IML和A5儿茶酚胺细胞组中未观察到标记的神经元。在我们之前的研究中，我们已经定义了泪道和下颌下分支之间的关系，而在本研究中，我们定义了泪道和SSN的泪道分支之间的关系：后者位于ISN的尾侧腹侧。在这些数据的基础上，给出了一个三维地形图，说明了ISN和SSN之间的关系。
In major brain maps the location of the salivatory nuclei of the rat is depicted from the level of the root of the facial nerve to the level of the rostral tip of the nucleus of the solitary tract. Most published data deal with the superior salivatory nucleus (SSN). In the present study the topography of the parasympathetic preganglionic neurons of the inferior salivatory nucleus (ISN) that innervate the parotid gland through the otic ganglion was determined by means of a retrograde transneuronal labeling technique. Parasympathetic, sympathetic and sensory neurons were labeled following injection of the virus into the parotid gland. The majority of the ISN neurons were found dorsal to the facial motor nucleus, embedded in the parvocellular reticular formation. In addition to the ISN neurons, virus-labelled cells were present in the intermediolateral (IML) cell column of the thoracic spinal cord, in the brainstem catecholamine groups, and in medullary raphe neurons. The removal of the ipsilateral superior cervical ganglion prior to the virus injection into the parotid gland did not influence the labeling of the ISN neurons but labeled neurons were not observed in the IML and A5 catecholamine cell group. In our previous study we had defined the relationship between the lacrimal and submandibular subdivison of the SSN, while in the present study we defined the relationship between the ISN and the lacrimal subdivision of SSN: the later located ventrolaterally to the caudal portion of the ISN. On the basis of these data a three-dimensional topography is given suggesting the relationship between the ISN and SSN.