Excitotoxicity, apoptosis and neuropsychiatric disorders
Excitotoxicity, apoptosis and neuropsychiatric disorders
复制标题
DOI：
10.1016/s1471-4892(02)00002-4
复制
发表时间：
2003-02-01
影响因子：
4
通讯作者：
Olney, JW
中科院分区：
文献类型：
--
作者：
Olney, JW
近几十年来，人们对中枢神经系统细胞死亡机制的兴趣高涨。很多注意力都集中在两个细胞死亡过程兴奋性毒性和细胞毒性，并出现了许多混乱，关于如何一个涉及到其他，以及如何涉及到神经系统疾病。最近的研究结果揭示了这个问题上的新的光，特别是在体内细胞凋亡，和意见，是相反的流行的解释表示，特别是在新兴的细胞凋亡领域的调查。
In recent decades there has been an upsurge of interest in mechanisms of cell death in the central nervous system. Much attention has been focused on two cell death processes-excitotoxicity and apoptosis-and much confusion has arisen regarding how one relates to the other, and how either relates to neurological disorders. Recent findings shed new light on this issue, especially with respect to in vivo apoptosis, and views that are contrary to prevailing interpretations are expressed, especially in the burgeoning apoptosis field of inquiry.