Fast magnetization-driven preparation for imaging of contrast-enhanced coronary arteries during intra-arterial injection of contrast agent
Fast magnetization-driven preparation for imaging of contrast-enhanced coronary arteries during intra-arterial injection of contrast agent
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DOI：
10.1002/jmri.20728
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发表时间：
2006-11-01
影响因子：
4.4
通讯作者：
Tsekos, Nikolaos V.
中科院分区：
文献类型：
--
作者：
Gui, Dawei;Tsekos, Nikolaos V.
材料与方法：通过计算机优化，得到1)抑制长T-1背景物种的制备方案：1)抑制T-1=250MSEE的长T-1背景物种；2)使T-1为250毫秒的对比剂增强(CE)结构的M-z最大，并将T-1为250毫秒的对比度增强(CE)结构的M-z降低约30%。模型研究验证了优化序列的性能。冠状动脉造影(用于制备和图像采集的380毫秒)显示CE冠状动脉的信噪比(SNR)在13-15.5之间，对比噪声比(CNR)在6.3-7.1范围内。结论：本工作证明快速磁化驱动的制备方案可用于CE冠状动脉的快速成像，并能有效地饱和背景物质。
Purpose: To implement a short-duration magnetization preparation sequence, which consists of a saturation followed by multiple inversion pulses, for imaging of short-T-1 species and suppression of long-T-1 species.Materials and Methods: Computer optimizations were performed to derive preparation schemes that 1) suppress long-T-1 background species with T-1 >= 250 msee, 2) maximize the M-z of contrast-enhanced (CE) structures with T-1 250 msec, and about a 30% reduction for 20 msec < T-1 < 50 msec. The phantom studies validated the performance of the optimized sequences. Coronary artery angiograms (380 msec for preparation and image acquisition) demonstrated signal-to-noise ratios (SNRs) in the range of 13-15.5 and contrast-to-noise ratios (CNRs) in the range of 6.3-7.1 in the CE coronary vessels.Conclusion: This work demonstrates that fast magnetization-driven preparation schemes can be implemented for fast imaging of CE coronary vessels with efficient saturation of background species.