Types of stressors that increase susceptibility to the common cold in healthy adults
Types of stressors that increase susceptibility to the common cold in healthy adults
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DOI：
10.1037/0278-6133.17.3.214
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发表时间：
1998-05-01
影响因子：
4.2
通讯作者：
Gwaltney, JM
中科院分区：
文献类型：
--
作者：
Cohen, S;Frank, E;Gwaltney, JM
276 名志愿者完成了生活压力访谈和心理问卷调查，并提供了血液和尿液样本。然后给他们接种普通感冒病毒并监测疾病的发作。虽然七种急性压力生活事件（持续时间少于 1 个月）与患感冒无关，但严重的慢性压力源（1 个月或更长）与疾病风险大幅增加相关。这种关系主要归因于低收入或失业以及与家人或朋友之间持久的人际关系困难。慢性压力源与感冒易感性之间的关联无法用有压力的人和无压力的人在社交网络特征、性格、健康习惯或攻击前内分泌或免疫措施方面的差异来充分解释。
Two-hundred seventy-six volunteers completed a life stressor interview and psychological questionnaires and provided blood and urine samples. They were then inoculated with common cold viruses and monitored for the onset of disease. Although seven acute stressful life events (less than 1 month long) were not associated with developing colds, severe chronic stressors (1 month or longer) were associated with a substantial increase in risk of disease. This relation was attributable primarily to under- or unemployment and to enduring interpersonal difficulties with family or friends. The association between chronic stressors and susceptibility to colds could not be fully explained by differences among stressed and nonstressed persons in social network characteristics, personality, health practices, or prechallenge endocrine or immune measures.