Prevalence of anti-delta antibodies in pregnant women in Bandung, Indonesia.

Prevalence of anti-delta antibodies in pregnant women in Bandung, Indonesia.
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印度尼西亚万隆孕妇抗 δ 抗体的患病率。

DOI:
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发表时间:
1988
期刊:
Tropical and geographical medicine
影响因子:
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通讯作者:
A. Meheus
A. Meheus
中科院分区:
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文献类型:
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作者:
R. Vranckx;J. Reniers;A. Alisjahbana;W. Ngantung;E. Sugita;A. Meheus

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在世界许多地区,丁型肝炎病毒(HDV)感染的流行病学知识非常匮乏。三角洲感染的地方性被认为是通过社区中乙肝表面抗原(HBs)携带者的网络保持和传播的。在远东和太平洋地区,慢性乙肝表面抗原携带者的患病率居高不下。在一些地区(如中国的部分地区、斐济岛、萨摩亚),丁型肝炎病毒感染的标志物非常常见,而在其他地区(如台湾、泰国、中国的部分地区)几乎没有。在万隆地区(印度尼西亚西爪哇),我们在926名孕妇中发现26名(2.8%)乙肝表面抗原携带者。他们大多是慢性携带者(抗-HBc-IgM阴性)。尽管乙肝表面抗原在印尼人群中很常见,但我们没有发现任何抗-HD阳性。这一数据证明,印度尼西亚人口稠密地区尚未出现HDV感染的结论。
Knowledge of the epidemiology of hepatitis D virus (HDV)-infection is very scarce in many parts of the world. The endemicity of delta-infection is believed to be maintained and spread through the network of hepatitis B surface antigen (HBsAg) carriers in the community. In the Far East and the Pacific area, the prevalence of chronic HBsAg carriers is mostly high. Markers of HDV infection are very frequent in some regions (e.g. parts of China, Fiji Isles, Samoa), in other regions they are almost absent (e.g. Taiwan, Thailand, parts of China). In the Bandung region (West Java, Indonesia) we found 26 (2.8%) HBsAg carriers among 926 pregnant women. Most of them are chronic carriers (anti hepatitis B core (HBc) IgM negative). Although HBsAg is frequent in this Indonesian population, we could not find any anti-HD positive. This data warrants the conclusion that HDV infection has not yet been introduced in that densely populated area of Indonesia.