Total, insoluble and soluble dietary fibre intake in relation to blood pressure: the INTERMAP Study.
Total, insoluble and soluble dietary fibre intake in relation to blood pressure: the INTERMAP Study.
复制标题
DOI：
10.1017/s0007114515003098
复制
发表时间：
2015-11-14
期刊：
影响因子：
--
通讯作者：
Frost GS
中科院分区：
文献类型：
--
作者：
Aljuraiban GS;Griep LM;Chan Q;Daviglus ML;Stamler J;Van Horn L;Elliott P;Frost GS
前瞻性队列研究表明，纤维摄入量和CVD之间存在负相关，可能由血压（BP）介导。然而，关于纤维类型对BP的影响知之甚少。我们研究了总的，不溶性和可溶性纤维摄入量与BP的横截面关联。数据来自MAcro/微量营养素和血压的国际研究（INTERMAP），包括来自美国的2195名年龄在40 - 59岁之间的男性和女性。在四次访视期间，收集了八个BP，四个24小时饮食回忆和两个24小时尿液样本。计算调整生活方式和饮食混杂因素的线性回归模型，以估计总纤维和个别纤维摄入量每增加2个标准差的血压差异。多变量校正后，总纤维摄入量增加6.8 g/4184 kJ（6.8 g/1000 kcal）与收缩压（SBP; 95% CI − 2.97，− 0.41）降低1.69 mmHg相关，校正尿钾后降至-1.01 mmHg（95% CI − 2.35，0.34）。不溶性纤维摄入量增加4.6 g/4184 kJ（4.6 g/1000 kcal）与SBP降低1.81 mmHg相关（95% CI − 3.65，0.04），另外校正了可溶性纤维和尿钾排泄，而可溶性纤维与BP无关。生水果是总纤维和不溶性纤维的主要来源，其次是全谷物和蔬菜。总之，较高的纤维摄入量，特别是不溶性纤维，可能有助于降低血压，独立于与较高的富含纤维的食物摄入量相关的营养素。
Prospective cohort studies have shown inverse associations between fibre intake and CVD, possibly mediated by blood pressure (BP). However, little is known about the impact of types of fibre on BP. We examined cross-sectional associations with BP of total, insoluble and soluble fibre intakes. Data were used from the INTERnational study on MAcro/micronutrients and blood Pressure (INTERMAP) study, including 2195 men and women aged between 40 and 59 years from the USA. During four visits, eight BP, four 24 h dietary recalls and two 24 h urine samples were collected. Linear regression models adjusted for lifestyle and dietary confounders to estimate BP differences per 2 SD higher intakes of total and individual types of fibre were calculated. After multivariable adjustment, total fibre intake higher by 6·8 g/4184 kJ (6·8 g/1000 kcal) was associated with a 1·69 mmHg lower systolic blood pressure (SBP; 95 % CI −2·97, −0·41) and attenuated to −1·01 mmHg (95% CI −2·35, 0·34) after adjustment for urinary K. Insoluble fibre intake higher by 4·6 g/4184 kJ (4·6 g/1000 kcal) was associated with a 1·81 mmHg lower SBP (95 % CI −3·65, 0·04), additionally adjusted for soluble fibre and urinary K excretion, whereas soluble fibre was not associated with BP. Raw fruit was the main source of total and insoluble fibre, followed by whole grains and vegetables. In conclusion, higher intakes of fibre, especially insoluble, may contribute to lower BP, independent of nutrients associated with higher intakes of fibre-rich foods.