In natura heart rate variability predicts subsequent alcohol use in individuals in early recovery from alcohol use disorder.
In natura heart rate variability predicts subsequent alcohol use in individuals in early recovery from alcohol use disorder.
复制标题
自然地，心率变异性可以预测个体在酒精使用障碍早期恢复过程中随后的饮酒情况。
DOI：
10.1111/adb.13306
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发表时间：
2023
影响因子：
3.4
通讯作者：
Zhai,Xiadi
中科院分区：
文献类型：
--
作者：
Eddie,David;Wieman,Sarah;Pietrzak,Agata;Zhai,Xiadi
心率变异性（HRV）降低反映的自主神经自我调节功能受损是酒精使用障碍（AUD）的常见特征，并被认为会增加AUD复发风险。然而，到目前为止，还没有研究探讨寻求AUD恢复的个体中naturaHRV和随后的酒精使用之间的关联。在这项研究中，使用动态心电图对当前AUD恢复尝试的第一年的42名成人进行了4天的监测，随后使用时间轴随访进行了90天的酒精使用监测。心率变异性指数（独立变量）反映自主神经心脏参与计算心电图记录。根据时间轴随访计算酒精使用（因变量），并表示为戒酒天数百分比（PDA）。样本为73.81%的白色/欧洲裔美国人、19.05%的黑人/非洲裔美国人、4.76%的亚洲人和2.38%的其他种族/混合种族。正如预测的那样，在90天随访期间，副交感神经介导的HRV较高和心率较低与PDA较大相关。此外，这些指标与基线PDA之间的相互作用表明，较高的副交感神经介导的HRV和较低的心率减轻了基线和随访酒精使用之间的有害正相关。在模型中包括已知影响酒精使用和/或HRV的因素并没有有意义地改变他们的结果。研究结果与心理生理学理论相一致，该理论涉及AUD治疗结局中的自主自我调节功能，并表明选择HRV指标可能具有作为AUD早期恢复个体酒精使用失效风险指标的实用性。研究结果为这一人群的HRV生物反馈提供了理论支持，该人群可以锻炼支持自我调节的心理生理系统。
Impairment in autonomic self‐regulatory functioning reflected by reduced heart rate variability (HRV) is a common feature of alcohol use disorder (AUD) and is believed to heighten AUD relapse risk. However, to date, no study has explored associations betweenin naturaHRV and subsequent alcohol use among individuals seeking AUD recovery. In this study, 42 adults in the first year of a current AUD recovery attempt were monitored for 4 days using ambulatory electrocardiogram, followed by 90 days of alcohol use monitoring using timeline follow‐back. HRV indices (independent variables) reflecting autonomic neurocardiac engagement were calculated from electrocardiogram recordings. Alcohol use (dependent variable) was calculated from timeline follow‐back and expressed as per cent days abstinent (PDA). The sample was 73.81% White/European American, 19.05% Black/African American, 4.76% Asian, and 2.38% Other race/Mixed race. As predicted, higher parasympathetically mediated HRV and lower heart rate were associated with greater PDA over 90‐day follow‐up. Additionally, interactions between these measures and baseline PDA indicated higher parasympathetically mediated HRV and lower heart rate mitigated the deleterious positive association between baseline and follow‐up alcohol use. Including factors known to influence alcohol use and/or HRV in the models did not meaningfully alter their results. Findings are consistent with psychophysiological theories implicating autonomic self‐regulatory functioning in AUD treatment outcomes and suggest that select HRV indices may have utility as indicants of risk for alcohol use lapse in individuals in early AUD recovery. Findings provide theoretical support for HRV Biofeedback for this population, which exercises the psychophysiological systems that support self‐regulation.