Analysis of Polycyclic Aromatic Hydrocarbons Using Desorption Atmospheric Pressure Chemical Ionization Coupled to a Portable Mass Spectrometer
Analysis of Polycyclic Aromatic Hydrocarbons Using Desorption Atmospheric Pressure Chemical Ionization Coupled to a Portable Mass Spectrometer
复制标题
DOI：
10.1007/s13361-014-1029-2
复制
发表时间：
2015-02-01
影响因子：
3.2
通讯作者：
Cooks, R. Graham
中科院分区：
文献类型：
--
作者：
Jjunju, Fred P. M.;Maher, Simon;Cooks, R. Graham
解吸常压化学电离（DAPCI）在便携式质谱仪上实现，应用于多环芳烃（PAH）和烷基取代苯的直接检测。这些化合物在环境中的存在对人类和野生动物的健康构成重大威胁，因为它们具有致癌、有毒和致突变特性。因此，实验室外的即时检测对于在源头进行原位测量尤为重要。使用快速、高通量、微型手持式质谱仪，检测多种烷基取代苯和多环芳烃（即 1,2,3,5-四甲基苯、五甲基苯、六甲基苯、荧蒽、蒽、苯并[k]荧蒽、二苯并[a,h]蒽、苊、茚并[1,2,3-c,d]芘、使用串联质谱 (MS/MS) 在露天环境表面对 9-乙基芴和 1-苄基-3-甲基-萘进行了鉴定和表征。该方法可以提供几乎即时的信息，同时最大限度地减少样品制备，这在成本和分析简单性方面都是有利的。这种基于质谱的技术适用于多种环境有机分子。
Desorption atmospheric pressure chemical ionization (DAPCI) is implemented on a portable mass spectrometer and applied to the direct detection of polycyclic aromatic hydrocarbons (PAHs) and alkyl substituted benzenes. The presence of these compounds in the environment poses a significant threat to the health of both humans and wildlife because of their carcinogenic, toxic, and mutagenic properties. As such, instant detection outside of the laboratory is of particular importance to allow in-situ measurement at the source. Using a rapid, high throughput, miniature, handheld mass spectrometer, several alkyl substituted benzenes and PAHs (i.e., 1,2,3,5-tetramethylbenzene, pentamethylbenzene, hexamethylbenzene, fluoranthene, anthracene, benzo[k]fluoranthene, dibenz[a,h]anthracene, acenaphthene, indeno[1,2,3-c,d]pyrene, 9-ethylfluorene, and 1-benzyl-3-methyl-naphthalene) were identified and characterized using tandem mass spectrometry (MS/MS) from ambient surfaces, in the open air. This method can provide almost instantaneous information while minimizing sample preparation, which is advantageous in terms of both cost and simplicity of analysis. This MS-based technique is applicable to a wide range of environmental organic molecules.