[Deposition of particles in the respiratory tract].
[Deposition of particles in the respiratory tract].
复制标题
[呼吸道中颗粒的沉积]。
DOI：
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复制
发表时间：
2001
期刊：
影响因子：
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通讯作者：
F. Lieutier
中科院分区：
文献类型：
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作者：
F. Lieutier
为了评估颗粒气溶胶在气道中的沉积位置，重要的是通过粒度范围分析来分析形成气溶胶的颗粒的粒度分布。涉及气溶胶沉积的三种主要不同机制是惯性碰撞、沉降和布朗扩散，根据吸入气溶胶的大小，其中一种或另一种占主导地位。最后，有几个因素可能影响呼吸道中的沉积：气道的解剖结构、呼吸方法、气溶胶的大小范围和含水量、吸烟和呼吸病理学。只有考虑到所有这些因素，才能对吸入颗粒在气道中的沉积部位进行评估。
In order to appraise the site of deposition of an aerosol of particles in the airways, it is important to analyse the size distribution of the particles that form the aerosol by granule size range analysis. The three main different mechanisms involved in deposition of an aerosol are inertia impaction, sedimentation and brownian diffusion, and one or another predominates, according to the size of the inhaled aerosol. Finally, several factors may influence the deposition in the respiratory tract: anatomy of the airways, the respiratory method, the size range and the moisture content of the aerosol, smoking and respiratory pathology. Only by taking into account all these factors can an assessment be made of the deposition site in the airways of the inhaled particles.