The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation
The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation
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DOI：
10.1111/cns.12428
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发表时间：
2015-09
影响因子：
5.5
通讯作者：
Wei-ming Wang;Zhao Liu;Ai-Jun Liu;Yu-xiang Wang;Hong-Gang Wang;Di An;Bin Heng;Lai-Hua Xie;Jun-Li Duan;Yan-qiang Liu
中科院分区：
文献类型：
--
作者：
Wei-ming Wang;Zhao Liu;Ai-Jun Liu;Yu-xiang Wang;Hong-Gang Wang;Di An;Bin Heng;Lai-Hua Xie;Jun-Li Duan;Yan-qiang Liu
我们的目的是确定TPEN，锌离子螯合剂，在介导的病理生理级联在缺氧/缺血诱导的神经元死亡/凋亡的显着效果。
We aim to determine the significant effect of TPEN, a Zn2+ chelator, in mediating the pathophysiological cascade in neuron death/apoptosis induced by hypoxia/ischemia.