Primary aldosteronism: making sense of partial data sets from failed adrenal venous sampling-suppression of adrenal aldosterone production can be used in clinical decision making
Primary aldosteronism: making sense of partial data sets from failed adrenal venous sampling-suppression of adrenal aldosterone production can be used in clinical decision making
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DOI：
10.1016/j.surg.2017.10.012
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发表时间：
2018-04-01
期刊：
影响因子：
3.8
通讯作者：
McKenzie, Travis J.
中科院分区：
文献类型：
--
作者：
Strajina, Veljko;Al-Hilli, Zahraa;McKenzie, Travis J.
背景资料。有人建议，对于原发性醛固酮增多症(PA)患者，在肾上腺静脉插管失败的情况下，可以做出准确的临床决定，从而仅利用右或左肾上腺静脉采样(AVS)的数据。对所有成功行双侧动静脉曲张的PA患者进行了回顾性分析。肾上腺静脉/下腔静脉指数(AV/IVC指数)是用肾上腺静脉的醛固酮/皮质醇比值除以下腔静脉的醛固酮/皮质醇比值来计算的，如先前发表的一项研究所述。我们检查了不适当的肾上腺切除和未能识别单侧疾病的比率，当使用先前公布的截断值时。150名患者符合纳入标准；61名患者为双侧，89名为单侧疾病。AV/IVC指数截止值为
Background. It has been suggested that accurate clinical decisions may be made in patients with primary aldosteronism (PA) in the setting of failed cannulation of an adrenal vein, thereby utilizing only data from either right or left adrenal venous sampling (AVS) alone.Methods. Retrospective analysis was performed for all patients with PA who underwent successful bilateral AVS. Adrenal vein/inferior vena cava index (AV/IVC index) was calculated by dividing aldosterone/cortisol ratio of the adrenal vein by aldosterone/cortisol ratio in the inferior vena cava, as described in a previously published study. We examined the rates of inappropriate adrenalectomy and failure to recognize unilateral disease when previously published cutoffs are used.Results. Inclusion criteria were met in 150 patients; 61 with bilateral and 89 with unilateral disease. AV/IVC index cutoff of