Age-related associations between substance use and sexual risk behavior among high-risk young African American women in the South.
Age-related associations between substance use and sexual risk behavior among high-risk young African American women in the South.
复制标题
南方高危年轻非裔美国女性物质使用与性危险行为之间的年龄相关性。
DOI：
10.1016/j.addbeh.2019.04.031
复制
发表时间：
2019
影响因子：
4.4
通讯作者：
Haardörfer,Regine
中科院分区：
文献类型：
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作者：
Swartzendruber,Andrea;Brown,JenniferL;Sales,JessicaM;Windle,Michael;Haardörfer,Regine
背景我们利用三项招募年轻非裔美国女性的艾滋病毒预防试验的数据，评估了物质使用和性危险行为之间与年龄相关的关联。方法我们使用综合数据分析来汇集 1862 名 16-25 岁个体的数据。我们使用时变效应模型来检查物质使用（每月酒精饮料、最近吸食大麻、每天吸烟）和性危险行为（每月阴道性交频率、多个性伴侣、无安全套性行为）之间的关联，并调整试验的固定效应。结果在包含所有三种物质的模型中，吸烟与任何结果均无关。酒精量与所有年龄段的性行为频率增加、17-24 岁左右拥有多个性伴侣的可能性增加以及 18.5 岁左右无安全套性行为的可能性增加相关。饮酒量和性行为频率之间的关联相对稳定；从 22 岁左右开始，与拥有多个性伴侣和无安全套性行为的关联性增加。大麻的使用与 16.5-24 岁左右的性行为频率增加有关，并且与 18-24 岁之间拥有多个性伴侣的可能性增加有关。与性行为频率的关联相对稳定；与拥有多个性伴侣的关联从 18 岁左右开始增加，并在 23 岁左右达到顶峰。结论我们观察到酒精和大麻与性危险行为之间存在发育依赖性关系。研究结果强调需要解决年轻非洲裔美国女性中与物质相关的性风险，并可能为干预的最佳时机提供信息。
BackgroundWe assessed age-related associations between substance use and sexual risk behavior using data from three HIV prevention trials that enrolled young African American women.MethodsWe used integrative data analysis to pool data from 1862 individuals aged 16–25 years. We used time-varying effect models to examine associations between substance use (alcoholic drinks per month, recent marijuana use, cigarettes smoked per day) and sexual risk behaviors (monthly frequency of vaginal sex, multiple sex partners, condomless sex), adjusting for the fixed effect of trial.ResultsIn models that included all three substances, cigarette smoking was not associated with any outcome. Alcohol quantity was associated with greater frequency of sex at all ages, an increased likelihood of having multiple sex partners from about age 17–24 years, and an increased likelihood of condomless sex after about age 18.5 years. Associations between alcohol quantity and sex frequency were relatively stable; associations with having multiple sex partners and condomless sex increased beginning at about age 22 years. Marijuana use was associated with greater sex frequency at approximate ages 16.5–24 years and an increased likelihood of having multiple sex partners at ages 18–24 years. Associations with sex frequency were relatively stable; associations with having multiple sex partners increased from about age 18 and peaked at about age 23 years.ConclusionsWe observed developmentally-dependent relationships between both alcohol and marijuana and sexual risk behavior. The findings underscore the need to address substance-related sexual risk among young African American women and may inform optimal timing of intervention.