Comprehensive Evaluation of Fetal Cardiac Ventricular Widths and Ratios Using a 24-Segment Speckle Tracking Technique
Comprehensive Evaluation of Fetal Cardiac Ventricular Widths and Ratios Using a 24-Segment Speckle Tracking Technique
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DOI：
10.1002/jum.14792
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发表时间：
2019-04-01
影响因子：
2.3
通讯作者：
Sklansky, Mark
中科院分区：
文献类型：
--
作者：
DeVore, Greggory R.;Cuneo, Bettina;Sklansky, Mark
引言本研究旨在评价右心室和左心室24个节段的横向宽度，并计算每个节段的右心室（RV）/左心室（LV）比值。方法对200例孕20 ~ 40周的正常胎儿进行检查。使用离线斑点追踪软件，计算24个舒张末期横向宽度，并将RV/LV比值与胎儿大小、体重和年龄相关的7个自变量进行回归。对5例主动脉缩窄胎儿和5例肺动脉狭窄胎儿进行了检查，以验证这些测量的实用性。结果：24段横宽与胎儿大小、体重和年龄的变化相关。开发回归方程来描述这些变化，R-2值在0.5和0.82之间。测量值呈正态分布（Shapiro-Wilk > 0.5）。24个节段的RV/LV比值与胎儿大小、体重或胎龄没有强相关性（R-2 = 0.001至-0.2）。患有主动脉缩窄和肺动脉狭窄的胎仔表现出心室基底（第1-8段）、中段（第9-16段）和心尖（第17-24段）24段横向宽度和RV/LV比值的特征性变化。结论左、右心室24节段横径及RV/LV比值是一种较全面的评价心室宽度的方法。
Introduction This study was conducted to evaluate the 24-segment transverse widths of the right and left ventricles distributed from the base to the apex of the ventricular chambers and compute the right ventricular (RV)/left ventricular (LV) ratios for each segment. Methods Two hundred control fetuses were examined between 20 and 40 weeks' gestation. Using offline speckle-tracking software, the 24 end-diastolic transverse widths were computed and the RV/LV ratios were regressed against 7 independent variables related to the size, weight, and age of the fetuses. Five fetuses with coarctation of the aorta and 5 fetuses with pulmonary stenosis were examined to exemplify the utility of these measurements. Findings The 24-segment transverse widths were associated with changes in fetal size, weight, and age. Regression equations were developed to describe these changes with R-2 values between .5 and .82. The measurements were normally distributed (Shapiro-Wilk > 0.5). The RV/LV ratio for the 24 segments did not strongly correlate (R-2 = .001 to -.2) with fetal size, weight, or gestational age. Fetuses with coarctation of the aorta and pulmonary stenosis demonstrated characteristic changes in the 24-segment transverse widths and the RV/LV ratios in the basal (segments 1-8), mid (segments 9-16) and apical (segments 17-24) sections of the ventricles. Conclusions The 24-segment transverse widths of the right and left ventricles and the RV/LV ratios provide a comprehensive method to examine the width of the ventricular chambers.