Ischemic cerebral edema. Distribution of water in brains of cats after occlusion of the middle cerebral artery.
Ischemic cerebral edema. Distribution of water in brains of cats after occlusion of the middle cerebral artery.
复制标题
缺血性脑水肿。
DOI：
10.1001/archneur.1974.00490360032007
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发表时间：
1974
影响因子：
--
通讯作者：
M. M. Jordan
中科院分区：
文献类型：
--
作者：
M. O'brien;A. G. Waltz;M. M. Jordan
在猫大脑中动脉闭塞后4小时至20天，测量了猫大脑样本的含水量。样本被分类为非缺血性（来自闭塞动脉对面的半球）、缺血性或梗死，主要是灰质或白质。与假手术猫的样本相比，在闭塞后4小时至3天，六种组织（包括来自非缺血半球的组织）的含水量均有所增加。这种增长在两天内达到最大。在任何时候，梗死组织的含水量都最大，非缺血组织的含水量最少，但从4到20天，差异很小。因此，单侧实验性脑缺血导致双侧脑水肿，这是暂时性的，在梗死区和缺血区更为明显。
Water content was measured in samples of brain obtained from cats four hours to 20 days after occlusion of one middle cerebral artery. Samples were categorized as nonischemic (from hemispheres opposite occluded arteries), ischemic, or infarcted, and as predominantly gray or white matter. When compared with samples from cats with sham operations, water content of each of the six types of tissue (including those from nonischemic hemispheres) was increased at four hours to three days after occlusion. The increase was maximal at two days. At all times, water content was greatest in infarcted tissue and least in nonischemic tissue, but from 4 to 20 days, differences were slight. Thus, unilateral experimental cerebral ischemia causes bilateral cerebral edema that is transient and more pronounced in infarcted and ischemic regions.