Activity loss and depression in age-related macular degeneration.
Activity loss and depression in age-related macular degeneration.
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年龄相关性黄斑变性的活动丧失和抑郁。
DOI：
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
R. Casten
中科院分区：
文献类型：
--
作者：
B. Rovner;R. Casten
视网膜相关性黄斑变性（AMD）是老年人严重视力丧失的最常见原因，并与高残疾率和抑郁症相关。作者评价了51例双侧AMD患者，以研究疾病严重程度、残疾和抑郁的相互关系，并重点关注作为AMD标志性残疾后果的有价值活动的丧失。他们通过流行病学抑郁症中心（CES-D）评分（基于CES-D的综合征状态）和痛苦水平（情感痛苦指数; IAS）来表征抑郁症。30名受试者（58.8%）丧失了有价值的自主活动。他们有更差的视力和更多的抑郁症状，并在更高的IAS水平比其他科目。视力与IAS水平显著相关，但与CES-D评分或综合征抑郁症无关。回归模型表明，活动损失介导的视力和IAS水平之间的关系。情感困扰发生在AMD中，很大程度上是因为视力丧失而放弃了有价值的活动。IAS水平最好地阐明了这种关系，这表明在慢性疾病后果的研究中情感功能的这一维度的价值。
Age-related macular degeneration (AMD) is the most frequent cause of severe vision loss in older persons and is associated with high rates of disability and depression. The authors evaluated 51 patients with bilateral AMD to investigate the interrelationships of disease severity, disability, and depression and focused on loss of valued activities as an emblematic disabling consequence of AMD. They characterized depression by the Center for Epidemiologic Studies-Depression (CES-D) score, a syndromal state based on the CES-D, and as a level of distress (Index of Affective Suffering; IAS). Thirty subjects (58.8%) had loss of a valued, discretionary activity. They had worse visual acuity and more depressive symptoms and were represented in higher IAS levels than other subjects. Visual acuity was significantly correlated with IAS levels, but not with CES-D scores or syndromal depression. A regression model demonstrated that activity loss mediated the relationship between visual acuity and IAS level. Affective distress occurs in AMD, largely to the extent that valued activities are relinquished because of vision loss. IAS levels best illuminated this relationship, suggesting the value of this dimension of affective functioning in studies of the consequences of chronic disease.
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抑郁症与残疾之间的关联。
DOI：
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发表时间：
1999
期刊：
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
影响因子：
--
作者：
Bruce,ML
通讯作者：
Bruce,ML
扩展抑郁情绪的活动限制模型：来自乳腺癌患者样本的证据。
DOI：
--
发表时间：
2000
期刊：
Health psychology : official journal of the Division of Health Psychology, American Psychological Association.
影响因子：
--
作者：
Williamson,GM
通讯作者：
Williamson,GM
影响因子：
120.7
作者：
Penninx, BWJH;Guralnik, JM;Wallace, RB
通讯作者：
Wallace, RB
综合医学和心理症状：对关节炎患者残疾和医疗保健利用的影响。
影响因子：
3
作者：
Vali,FM;Walkup,J
通讯作者：
Walkup,J