Biaryl Cross‐Coupling Enabled by Photo‐Induced Electron Transfer
Biaryl Cross‐Coupling Enabled by Photo‐Induced Electron Transfer
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DOI：
10.1002/adsc.201901601
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发表时间：
2020-05
影响因子：
5.4
通讯作者：
Hirohito Hayashi;Bin Wang;Xiangyang Wu;S. Teo;A. Kaga;Kohei Watanabe;Ryo Takita;E. K. Yeow;S. Chiba
中科院分区：
文献类型：
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作者：
Hirohito Hayashi;Bin Wang;Xiangyang Wu;S. Teo;A. Kaga;Kohei Watanabe;Ryo Takita;E. K. Yeow;S. Chiba
我们报告了一种仅由紫光驱动的缺电子芳基卤化物与富电子（杂）芳烃的芳基交叉偶联方案。该过程利用了缺电子芳基卤化物的光激发态的形成，其被富电子（杂）芳烃还原以形成一对芳基阴离子和阳离子自由基。所得芳基卤化物的芳基阴离子自由基经历碳-卤素键的中分解以产生芳基自由基，其最有可能与芳基阳离子自由基偶联以提供官能化联芳基。
We report a protocol for aryl cross‐coupling of electron‐deficient aryl halides with electron‐rich (hetero)arenes that is driven solely by violet light. This process takes advantage of formation of photo‐excited state of electron‐deficient aryl halides, that are reduced by electron‐rich (hetero)arenes to form a pair of aryl anion and cation radicals. The resulting aryl anion radicals of aryl halides undergo mesolysis of the carbon‐halogen bond to generate aryl radicals, that are coupled most likely with aryl cation radicals to afford functionalized biaryls.