Effects of caffeine on glucose tolerance: A placebo-controlled study
Effects of caffeine on glucose tolerance: A placebo-controlled study
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咖啡因对葡萄糖耐量的影响：一项安慰剂对照研究
DOI：
10.1038/sj.ejcn.1600657
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发表时间：
1998
影响因子：
4.7
通讯作者：
A. Pessina
中科院分区：
文献类型：
--
作者：
A. Pizziol;V. Tikhonoff;C. D. Paleari;E. Russo;Alberto Mazza;G. Ginocchio;C. Onesto;L. Pavan;Edoardo Casiglia;A. Pessina
目的：研究口服200 mg咖啡因对葡萄糖耐量的影响。设计：单盲拉丁方，积极治疗（咖啡因）和安慰剂。设置：帕多瓦大学，内科。受试者：30名年龄26-32岁的非吸烟健康受试者，他们不仅戒咖啡，而且戒茶，巧克力和可乐4周，并给予知情同意。干预：75 g口服葡萄糖耐量试验（OGTT）进行后给予咖啡因或安慰剂（高度脱咖啡因咖啡）。结果：血液动力学曲线是正常的，在所有受试者和两组相似，直到第二个小时，在受试者服用咖啡因向右移动被检测到在第2，第3和第4小时相比，那些服用安慰剂。血液胰岛素水平相当咖啡因和安慰剂后沿着整个OGTT.Conclusions：数据表明，咖啡因摄入量引起的血糖水平上升，是胰岛素independent.Sponsor：临床和实验医学系，帕多瓦大学，意大利。
Objective: The investigation was performed to study the effects of 200 mg oral caffeine on glucose tolerance.Design: Single-blind Latin square with active treatment (caffeine) and placebo.Setting: The University of Padova, Department of Internal Medicine.Subjects: 30 nonsmoking healthy subjects aged 26–32 years who abstained not only from coffee but also from tea, chocolate and cola for 4 weeks and who had given their informed consent.Interventions: A 75 g oral glucose tolerance test (OGTT) was performed after giving caffeine or placebo (highly decaffeinated coffee).Results: The glycaemic curve was normal in all subjects and was similar in the two groups until the second hour; in subjects taking caffeine a shift towards the right was detected at the 2nd, 3rd and 4th hours in comparison to those taking the placebo. Blood insulin levels were comparable after caffeine and after placebo along the entire OGTT.Conclusions: The data suggest that caffeine intake induces a rise in blood glucose levels that is insulin independent.Sponsor: Department of Clinical and Experimental Medicine, University of Padova, Italy.
男性咖啡摄入量与胆固醇和载脂蛋白 B 水平升高。
DOI：
--
发表时间：
1985
期刊：
JAMA
影响因子：
--
作者：
Williams,PT;Wood,PD;Vranizan,KM;Albers,JJ;Garay,SC;Taylor,CB
通讯作者：
Taylor,CB