Randomized double masked trial of Zhi Byed 11, a Tibetan traditional medicine, versus misoprostol to prevent postpartum hemorrhage in Lhasa, Tibet.
Randomized double masked trial of Zhi Byed 11, a Tibetan traditional medicine, versus misoprostol to prevent postpartum hemorrhage in Lhasa, Tibet.
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DOI：
10.1016/j.jmwh.2008.09.010
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发表时间：
2009-03
影响因子：
2.7
通讯作者：
Varner, Michael W.
中科院分区：
文献类型：
--
作者：
Miller, Suellen;Tudor, Carrie;Thorsten, Vanessa;Nyima;Kalyang;Sonam;Lhakpen;Droyoung;Quzong, Karma;Dekyi, Tsering;Hartwell, Ty;Wright, Linda L.;Varner, Michael W.
The objective of this study was to compare a Tibetan traditional medicine (the uterotonic Zhi Byed 11 [ZB11]) to oral misoprostol for prophylaxis of postpartum hemorrhage (PPH). We conducted a double-blind randomized controlled trial at three hospitals in Lhasa, Tibet, People’s Republic of China. Women (N = 967) were randomized to either ZB11 or misoprostol groups. Postpartum blood loss was measured in a calibrated blood collection drape. The primary combined outcome was incidence of PPH, defined as measured blood loss (MBL) ≥ 500 mL, administration of open label uterotonics, or maternal death. We found that the rate of the combined outcome was lower among the misoprostol group (16.1% versus 21.8% for ZB11; P = .02). Frequency of PPH was lower with misoprostol (12.4% versus 17.4%; P = .02). There were no significant differences in MBL > 1000 mL or mean or median MBL. Fever was significantly more common in the misoprostol group (P = .03). The rate of combined outcome was significantly lower among women receiving misoprostol. However, other indices of obstetric hemorrhage were not significantly different.
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影响因子：
1.7
作者：
Adams, Vincanne;Miller, Suellen;Varner, Micheal
通讯作者：
Varner, Micheal
影响因子：
105.7
作者：
Hoj, L;Cardoso, P;Aaby, P
通讯作者：
Aaby, P
影响因子：
168.9
作者：
Derman, Richard J.;Kodkany, Bhalchandra S.;Moss, Nancy
通讯作者：
Moss, Nancy
DOI：
10.1016/0091-2182(84)90166-6
发表时间：
1984-01-01
期刊：
JOURNAL OF NURSE-MIDWIFERY
影响因子：
--
作者：
DAVIS, L
通讯作者：
DAVIS, L
影响因子：
1.9
作者：
OBRIEN, PC;FLEMING, TR
通讯作者：
FLEMING, TR