Castleman's disease mimicking a parotid gland tumor: report of a case and review of the literature.
Castleman's disease mimicking a parotid gland tumor: report of a case and review of the literature.
复制标题
卡斯尔曼病酷似腮腺肿瘤：一例报告及文献复习。
DOI：
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发表时间：
2014
影响因子：
3.3
通讯作者：
Luigi Califano
中科院分区：
文献类型：
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作者：
G. Iaconetta;M. Friscia;G. Orabona;S. D. Biasi;Antonio Romano;P. Piombino;P. Graziano;V. Abbate;G. Salzano;F. Maglitto;Luigi Califano
Castleman病(巨大淋巴结增生、血管滤泡性增生、淋巴错构瘤、良性巨大淋巴瘤)是一种罕见且复杂的淋巴组织疾病，导致进行性淋巴结肿大，典型表现为孤立性纵隔肿块。它最早是由Castleman等人在1956年描述的。头部和颈部是第二个不太常见的部位。术前诊断往往非常困难，常规检查往往不能得出结论。与单灶性组织学类型相比，多中心扩散型预后较差，存在三种类型：透明血管型、浆细胞型和混合型。其病因和发病机制尚不清楚。在文献中，据我们所知，只有112例报告涉及头和颈部，只有22例，包括我们自己，感兴趣的腮腺。在这篇报告中，我们描述了一位35岁女性罕见的Castleman病，表现为腮腺下极肿瘤，延伸至颌下区。患者接受了手术治疗，因此，肿块被成功地完全切除。
Castleman's disease (giant lymph node hyperplasia, angiofollicular hyperplasia, lymphoid hamartoma, benign giant lymphoma), is a quite rare and complex disease of lymphoid tissue that causes progressive lymph node enlargement, typically presenting as a solitary mediastinal mass. It was first described by Castleman et al in 1956. The head and neck regions are the second, less common site for this lesion. The preoperative diagnosis is very often extremely difficult and the routine investigations are often inconclusive. A multicentric extension of this disease shows poorer prognosis compared to the unifocal Histologically, three types do exist: the hyaline-vascular type, the plasma cell type and the mixed type. The etiology and pathogenesis is still unclear. In the literature, to our knowledge, only 112 cases have been reported involving head and neck, and only 22, including our own, interesting the parotid gland. In this report we describe a rare singular of Castleman's disease presenting as a tumor of the inferior pole of the parotid gland extending in the submandibular region, in a 35-year-old woman. The patient undergone a surgical treatment and, therefore, the mass was successfully totally removed.