Applications of Nanoparticles for Anticancer Drug Delivery: A Review.
Applications of Nanoparticles for Anticancer Drug Delivery: A Review.
复制标题
DOI：
10.1166/jnn.2015.10298
复制
发表时间：
2015-07
影响因子：
--
通讯作者：
Yuanyuan Zhu;L. Liao
中科院分区：
文献类型：
--
作者：
Yuanyuan Zhu;L. Liao
Biodegradable nanometer-sized particles have novel structural and physical properties that are attracting great interests from pharmaceuticals for the targeted delivery of anticancer drugs and imaging contrast agents. These smart nanoparticles are designed to ferry chemotherapeutic agents or therapeutic genes into malignant cells while sparing healthy cells. In this review, we describe currently clinically used chemotherapeutics in nanoparticle formulation and discuss the current status of nanoparticles developed as targeting delivery systems for anticancer drugs, with emphasis on formulations of micelles, liposome, polymeric nanoparticles, gold nanoparticle dendrimers, and bionanocapsules.
