mTORC1 inhibition restores autophagic flux by inhibitory phosphorylation of RIP1, leading to suppression of necroptosis in cardiomyocytes.
mTORC1 inhibition restores autophagic flux by inhibitory phosphorylation of RIP1, leading to suppression of necroptosis in cardiomyocytes.
复制标题
mTORC1 抑制可通过 RIP1 的抑制性磷酸化恢复自噬流,从而抑制心肌细胞的坏死性凋亡。
DOI:
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发表时间:
2018
期刊:
影响因子:
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通讯作者:
Miura T.
中科院分区:
文献类型:
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作者:
Abe K;Yano T;Ogasawara M;Miki T;Tanno M;Kuno A;Miura T.