Air filter materials, outdoor ozone and building-related symptoms in the BASE study
Air filter materials, outdoor ozone and building-related symptoms in the BASE study
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DOI：
10.1111/j.1600-0668.2008.00519.x
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发表时间：
2008-04-01
期刊：
影响因子：
5.8
通讯作者：
Apte, M. G.
中科院分区：
文献类型：
--
作者：
Buchanan, I. S. H.;Mendell, M. J.;Apte, M. G.
研究表明，使用过的通风空气过滤器会降低室内环境质量和工人的工作表现，并增加症状，过滤器与臭氧反应后的影响更大。我们分析了美国环保局建筑评估调查和评估(BASE)研究的数据，以确定臭氧和特定的过滤介质是否对建筑相关症状(BRS)产生交互影响。我们分析了美国100栋写字楼基础研究中34栋建筑的子集，以确定过滤介质[聚酯/合成(PS)或玻璃纤维(FG)]和室外臭氧浓度(高于/低于中位数，67.6微克/米(3))与BRS的单独和联合关联。使用Logistic回归模型和一般估计方程，我们估计了过滤介质、臭氧和过滤介质x与BRS的关联的优势比(ORs)和95%的可信区间。相对于FG+低臭氧、单独PS或单独高浓度臭氧，仅与疲劳/难以集中有关(P<；0.05)(OR分别为1.93和1.54)。然而，与FG+低臭氧相比，PS+高臭氧联合暴露与下呼吸道和上呼吸道、咳嗽、眼睛、疲劳和头痛BRS有显著关联(OR值从2.26到5.90)。PS+高臭氧对下、上呼吸道和头痛BRS的联合OR值远大于乘法，交互作用P值为0.10。归因风险比例(ARP)估计表明，在某些假设下，剔除这两个风险因素可能会使BRS减少26%-62%。这些发现表明，室外臭氧和建筑物中PS过滤器之间的化学相互作用可能会对健康造成不利影响。在建议对建筑运营进行更改之前，需要确认结果。然而，如果更多的研究证实了因果关系，ARP估计表明，适当的过滤器选择可能会大大减少建筑物中的BRS，特别是在臭氧含量高的地区。
Used ventilation air filters have been shown to reduce indoor environmental quality and worker performance and increase symptoms, with effects stronger after reaction of filters with ozone. We analyzed data from the US EPA Building Assessment Survey and Evaluation (BASE) study to determine if ozone and specific filter media have interactive effects on building-related symptoms (BRS). We analyzed a subset of 34 buildings from the BASE study of 100 US office buildings to determine the separate and joint associations of filter medium [polyester/synthetic (PS) or fiberglass (FG)] and outdoor ozone concentration (above/below the median, 67.6 mu g/m(3)) with BRS. Using logistic regression models and general estimating equations, we estimated odds ratios (ORs) and 95% confidence intervals for the association of filter medium, ozone, and filter medium x ozone with BRS. Relative to FG + low ozone, PS alone or high ozone alone, were each significantly (P < 0.05) associated only with fatigue/difficulty concentrating (ORs = 1.93 and 1.54, respectively). However, joint exposure to both PS + high ozone, relative to FG + low ozone, had significant associations with lower and upper respiratory, cough, eye, fatigue, and headache BRS (ORs ranged from 2.26 to 5.90). Joint ORs for PS + high ozone for lower and upper respiratory and headache BRS were much greater than multiplicative, with interaction P-values < 0.10. Attributable risk proportion (ARP) estimates indicate that removing both risk factors might, given certain assumptions, reduce BRS by 26-62%. These findings suggest possible adverse health consequences from chemical interactions between outdoor ozone and PS filters in buildings. Results need confirmation before recommending changes in building operation. However, if additional research confirms causal relationships, ARP estimates indicate that appropriate filter selection may substantially reduce BRS in buildings, especially in high-ozone areas.