Electrochemical Characterization of Glucose Bioanodes Based on Tetramethylferrocene-Modified Linear Poly(ethylenimine)
Electrochemical Characterization of Glucose Bioanodes Based on Tetramethylferrocene-Modified Linear Poly(ethylenimine)
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DOI：
10.1016/j.electacta.2014.10.077
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发表时间：
2014-12-10
影响因子：
6.6
通讯作者：
Glatzhofer, Daniel T.
中科院分区：
文献类型：
--
作者：
Hickey, David P.;Halmes, Abigail J.;Glatzhofer, Daniel T.
四甲基二茂铁改性线性聚乙烯亚胺 (FcMe(4)-C-3-LPEI) 在葡萄糖氧化酶 (GOx) 存在下与乙二醇二缩水甘油醚 (EGDGE) 交联，形成酶促葡萄糖生物阳极，能够使用 3 mm 玻碳电极和 15.1 +/- 0.8 产生 1.034 +/- 0.039 mA/cm(2) mA/cm(2)，25 摄氏度下使用 0.5 x 0.5 cm 碳毡电极。FcMe(4)-C-3-LPEI/GOx 薄膜通过改变 EGDGE 量、pH 值和电极材料进行表征。结果表明，电化学电势随用于交联薄膜的 EGDGE 量的变化而变化，相对于使用 4 mol% 至 32 mol% EGDGE 的 SCE，电化学电势分别从 0.068 +/- 0.016V 到 0.122 +/- 0.003V。当 pH 值从 0.073 +/- 0.004V vs SCE（pH 4.0）变化到 pH 8.0 的 0.118 +/- 0.003 时，也出现了类似的趋势。本文描述的优化材料具有作为酶生物阳极和葡萄糖生物传感器的直接实际用途。 (C) 2014 Elsevier Ltd. 保留所有权利。
Tetramethylferrocene-modified linear(polyethylenimine) (FcMe(4)-C-3-LPEI) was cross-linked with ethylene glycol diglycidyl ether (EGDGE) in the presence of glucose oxidase (GOx) to form enzymatic glucose bioanodes capable of generating 1.034 +/- 0.039 mA/cm(2) with 3 mm glassy carbon electrodes and 15.1 +/- 0.8 mA/cm(2) with 0.5 x 0.5 cm carbon felt electrodes at 25 degrees C. FcMe(4)-C-3-LPEI/GOx films were characterized by varying the amount of EGDGE, pH, and electrode material. The electrochemical potential was shown to vary with the amount of EGDGE used to cross-link the film, from 0.068 +/- 0.016V to 0.122 +/- 0.003V vs SCE using 4 mol% to 32 mol% EGDGE respectively. A similar trend occurred upon varying pH from 0.073 +/- 0.004V vs SCE at pH 4.0 to 0.118 +/- 0.003 at pH 8.0. The optimized materials described herein have direct practical use as enzymatic bioanodes and as glucose biosensors. (C) 2014 Elsevier Ltd. All rights reserved.