Optimized workflow and imaging protocols for whole-body oncologic PET/MRI
Optimized workflow and imaging protocols for whole-body oncologic PET/MRI
复制标题
DOI：
10.1007/s11604-016-0584-9
复制
发表时间：
2016-11-01
影响因子：
2.1
通讯作者：
Ito, Hiroshi
中科院分区：
文献类型：
--
作者：
Ishii, Shirou;Hara, Takamitsu;Ito, Hiroshi
尽管PET/MRI具有同时采集PET和MRI、MRI图像软组织对比度高、减少辐射暴露等优点，但其盈利能力低和采集时间长是临床环境中的重大问题。因此，需要使用满足肿瘤学目的的 MRI 协议，以减少检查时间，同时确保可检测性。目前，半傅里叶采集单次涡轮自旋回波和3D-T1体积插值屏气检查可能是全身成像最常用的序列，因为它们的采集时间更短，诊断精度更高。尽管有几份报告表明，迄今为止，在 PET/MRI 协议中添加弥散加权图像 (DWI) 对肿瘤检测没有影响，但在肝癌、肾癌、膀胱癌和前列腺癌的情况下，使用 DWI 可能有利于检测病变。另一种可能的选择是使用不同的 MRI 序列扫描每个区域，而不是使用一个序列连续扫描整个身体。我们在此报告了在临床常规中使用集成系统进行全身肿瘤 PET/MRI 的工作流程和成像方案，该系统旨在通过癌症筛查等方式检测转移性病变，以帮助未来用户优化其工作流程和成像方案。
Although PET/MRI has the advantages of a simultaneous acquisition of PET and MRI, high soft-tissue contrast of the MRI images, and reduction of radiation exposure, its low profitability and long acquisition time are significant problems in clinical settings. Thus, MRI protocols that meet oncological purposes need to be used in order to reduce examination time while securing detectability. Currently, half-Fourier acquisition single-shot turbo spin echo and 3D-T1 volumetric interpolated breath-hold examination may be the most commonly used sequences for whole-body imaging due to their shorter acquisition time and higher diagnostic accuracy. Although there have been several reports that adding diffusion weighted image (DWI) to PET/MRI protocol has had no effect on tumor detection to date, in cases of liver, kidney, bladder, and prostate cancer, the use of DWI may be beneficial in detecting lesions. Another possible option is to scan each region with different MRI sequences instead of scanning the whole body using one sequence continuously. We herein report a workflow and imaging protocols for whole-body oncologic PET/MRI using an integrated system in the clinical routine, designed for the detection, for example by cancer screening, of metastatic lesions, in order to help future users optimize their workflow and imaging protocols.