Proteomic profiling of aging in the mouse heart: Altered expression of mitochondrial proteins
Proteomic profiling of aging in the mouse heart: Altered expression of mitochondrial proteins
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DOI：
10.1016/j.abb.2008.02.001
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发表时间：
2008-06-01
影响因子：
3.9
通讯作者：
Chakravarti, Deb N.
中科院分区：
文献类型：
--
作者：
Chakravarti, Bulbul;Oseguera, Melva;Chakravarti, Deb N.
利用双向凝胶电泳和液相色谱-串联质谱技术，我们用系统生物学方法研究了小鼠心脏衰老的分子基础。我们鉴定了8个蛋白质点的表达由于衰老而上调，36个蛋白质点的表达由于衰老而下调（p
Using two-dimensional gel electrophoresis and liquid chromatography-tandem mass spectrometry, we have used a systems biology approach to study the molecular basis of aging of the mouse heart. We have identified 8 protein spots whose expression is up-regulated due to aging and 36 protein spots whose expression is down-regulated due to aging (p