Do laboratory tests of blood pressure reactivity predict blood pressure changes during everyday life?
Do laboratory tests of blood pressure reactivity predict blood pressure changes during everyday life?
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血压反应性的实验室测试能否预测日常生活中的血压变化？
DOI：
10.1093/ajh/1.2.168
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发表时间：
1988
影响因子：
3.2
通讯作者：
Pickering,TG
中科院分区：
文献类型：
--
作者：
Harshfield,GA;James,GD;Schlussel,Y;Yee,LS;Blank,SG;Pickering,TG
本研究旨在检验在实验室受控环境中测量的血压反应性是否与日常生活中发生的血压变化相关。受试者为164名未经治疗的轻度高血压患者，所有受试者均进行了24小时动态血压记录，期间活动不受限制。 113 人进行了跑步机运动测试，51 人进行了两项主动应对任务（玩电子游戏或心算）。在基线和任务期间监测血压。在实验室测试和动态监测期间测量的压力绝对水平之间观察到显着相关性，但主动应对任务（r = 0.53至0.75）的绝对压力水平高于运动测试（r = 0.26至0.46），并且任务期间测量的压力并不高于基线。使用简单相关、多重相关和典型相关，以三种方式分析实验室任务期间血压变化与动态监测期间发生的变化之间的相关性。在任何情况下，这些相关性都不具有实质性显着性。我们的结论是，实验室测量的血压反应性可能不容易推广到日常生活中的压力变化，如无创动态记录仪测量的那样。美国高血压杂志 1988； 1：168-174。
This study was undertaken to examine whether bloodpressure reactivity measured in the controlled setting of alaboratory could be correlated with blood pressurechanges occurring during daily life. The subjects were164 untreated hypertensives with mild hypertension, allof whom had a 24-hour ambulatory blood pressurerecording, during which their activities were unrestricted. One hundred thirteen performed a treadmill exercise test, and 51 performed two active coping tasks (playing avideo game or mental arithmetic). Blood pressure wasmonitored at baseline and during the tasks.Significant correlations were observed between theabsolute levels of pressure measured during the laboratorytests and ambulatory monitoring, but these werehigher for the active coping tasks (r = 0.53 to 0.75) thanthe exercise testing (r = 0.26 to 0.46) and were no higherfor pressures measured during the tasks than at baseline. Correlations between the changes of blood pressureduring the laboratory tasks and the changes occurringduring ambulatory monitoring were analyzed in threeways, using simple, multiple, and canonical correlations. In no case were these correlations substantively significant. We conclude that blood pressure reactivity measuredin the laboratory may not be readily generalized tochanges of pressure in everyday life, as measured bynoninvasive ambulatory recorders. Am J Hypertens 1988; 1:168-174.