Elevated blood Hg at recommended seafood consumption rates in adult seafood consumers
Elevated blood Hg at recommended seafood consumption rates in adult seafood consumers
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DOI：
10.1016/j.ijheh.2014.03.007
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发表时间：
2014-09-01
影响因子：
6
通讯作者：
Meliker, Jaymie R.
中科院分区：
文献类型：
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作者：
Karimi, Roxanne;Silbernagel, Susan;Meliker, Jaymie R.
海产品汞暴露仍然是一个公共卫生问题，因为暴露增加、全球海产品消费量增加以及环境中汞的持续输入对健康造成了影响。汞暴露增加可能发生在专门食用运动捕获的淡水鱼的人群中。然而，我们需要更好地了解来自海鲜的汞暴露情况，海鲜是最常见的接触来源，以及特定的海鲜类型。我们检查了狂热的海鲜消费者的汞暴露情况，以及导致汞暴露最大的海鲜项目和消费频率。在美国纽约州长岛，血液总汞浓度预计超过被认为安全的美国环保局参考浓度(5.8mgL-1)的成年狂热海鲜消费者有资格参加这项研究；75%的自我报告的狂热海鲜消费者有资格参与。我们测量了285名参与者的血液总汞浓度和海鲜摄入量。我们使用多元线性回归检验了汞和海鲜消费之间的关系。我国人口的海鲜消费量(14.4公斤年(-1))是美国估计(6.8公斤年(-1))的2倍，低于世界估计(18.4公斤年(-1))。平均血汞浓度是全国平均水平的4.4倍，42%的参与者汞浓度超过5.8mg L-1。汞暴露增加发生在所有海鲜消费频率，包括建议的每周两餐的频率。血汞浓度与每周摄入金枪鱼牛排或寿司(β=6.3血汞变化，单位L-1)、每月(β=2.54)或每周(β=9.47)旗鱼、鲨鱼或马林鱼的摄入量呈正相关。我们的发现表明，该人群中的海鲜消费者即使在相对较低的海鲜消耗率处于或低于当前饮食建议的情况下，汞暴露也会增加。进一步研究应审查食用海鲜对健康的风险和益处，并考虑修改指南，以纳入对特定海鲜类型的建议。(C)2014年爱思唯尔股份有限公司。版权所有。
Mercury (Hg) exposure from seafood continues to be a public health concern due to health effects from elevated exposure, increasing worldwide seafood consumption, and continued Hg inputs into the environment. Elevated Hg exposure can occur in populations with specialized diets of sport-caught freshwater fish. However, we need a better understanding of Hg exposure from seafood, the most common exposure source, and from specific seafood types. We examined Hg exposure in avid seafood consumers, and the seafood items and consumption frequency that confer the largest Hg exposure. Adult, avid seafood consumers, in Long Island, NY, USA, with blood total Hg concentrations predicted to exceed the USEPA reference concentration that is considered safe (5.8 mu g L-1), were eligible for the study; 75% of self-reported avid seafood consumers were eligible to participate. We measured blood total Hg concentrations and seafood consumption in 285 participants. We examined relationships between Hg and seafood consumption using multiple linear regression. Seafood consumption rate for our population (14.4 kg yr(-1)) was >2 times that estimated for the U.S. (6.8 kg yr(-1)), and lower than the worldwide estimate (18.4 kg yr(-1)). Mean blood Hg concentration was 4.4 times the national average, and 42% of participants had Hg concentrations exceeding 5.8 mu g L-1. Elevated Hg exposures occurred at all seafood consumption frequencies, including the recommended frequency of 2 meals per week. Blood Hg concentrations were positively associated with weekly tuna steak or sushi intake (beta = 6.30 change in blood Hg, mu g L-1) and monthly (beta = 2.54) or weekly (beta = 9.47) swordfish, shark or marlin intake. Our findings show that seafood consumers in this population have elevated Hg exposures even at relatively low seafood consumption rates that are at or below current dietary recommendations. Further study should examine health risks and benefits of avid seafood consumption, and consider modifying guidelines to include recommendations for specific seafood types. (C) 2014 Elsevier GmbH. All rights reserved.