The electrocardiogram in right ventricular cardiomyopathy/dysplasia. How can the electrocardiogram assist in understanding the pathologic and functional changes of the heart in this disease?
The electrocardiogram in right ventricular cardiomyopathy/dysplasia. How can the electrocardiogram assist in understanding the pathologic and functional changes of the heart in this disease?
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DOI：
10.1016/j.jelectrocard.2008.12.011
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发表时间：
2009-03-01
影响因子：
1.3
通讯作者：
Zareba, Wojciech
中科院分区：
文献类型：
--
作者：
Marcus, Frank I;Zareba, Wojciech
心电图（ECG）为心律失常性右室心肌病/发育不良（ARVC/D）的诊断提供了重要信息。心电图的改变可以用疾病的病理生理来解释。右心室（RV）靠近前胸导联(V（1)至V(4)）解释了为什么特征性ECG异常在这些导联中最为突出。具体的心电图异常反映了疾病的病理生理，包括右心室自由壁瘢痕形成导致的t波反转，由于右心室是心脏最后一个去极化的部位，QRS末端去极化缓慢导致的s波持续时间延长，以及右心室传导缓慢导致的epsilon波。心电图异常的程度与右心室结构改变的程度相关。
The electrocardiogram (ECG) provides important information to aid in the diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D). The ECG changes may be explained by the pathophysiology of the disease. The proximity of the right ventricle (RV) to the anterior chest leads (V(1) to V(4)) explains why the characteristic ECG abnormalities are most prominent in those lends. The specific ECG abnormalities reflect the pathophysiology of the disease including T-wave inversion due to scarring of the free wall of the RV, prolonged S-wave duration due to slow depolarization of the terminal part of the QRS because the RV is the last part of the heart to undergo depolatization, and epsilon waves due to slow conduction in the RV. The extent of ECG abnormalities correlate with the degree of structural change in the RV.