Epidemiology and management of osteoporosis in the People's Republic of China: current perspectives.

Epidemiology and management of osteoporosis in the People's Republic of China: current perspectives.
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DOI:
10.2147/cia.s54613
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发表时间:
2015
影响因子:
3.6
通讯作者:
Liao EY
Liao EY
中科院分区:
医学2区
文献类型:
--
作者:
Lin X;Xiong D;Peng YQ;Sheng ZF;Wu XY;Wu XP;Wu F;Yuan LQ;Liao EY

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随着人口的逐步老龄化,骨质疏松症已逐渐发展成为50岁及以上男性和女性的全球性健康问题,因为其在残疾和脆性骨折方面的后果。尤其是在人口最多、老年人口比例不断增加的中华人民共和国,骨质疏松症已成为中国政府、社会和家庭面临的严峻挑战。除了所有骨质疏松性骨折都会增加患者的发病率之外,它们还可能导致髋部和椎骨骨折,这与显着更高的死亡率相关。此外,骨质疏松性骨折的费用是家庭、社会甚至国家的沉重负担,部分由于平均预期寿命的提高,这一费用在未来可能会增加。因此,了解骨质疏松症的流行病学是必不可少的,对于制定有助于减少这一问题的策略具有重要意义。本文综述了中华人民共和国骨质疏松症的流行病学,包括骨质疏松性骨折的流行病学,重点介绍了骨质疏松症的预防方法和管理,包括基本措施和药物治疗。
With the progressive aging of the population, osteoporosis has gradually grown into a global health problem for men and women aged 50 years and older because of its consequences in terms of disabilities and fragility fractures. This is especially true in the People’s Republic of China, which has the largest population and an increasing proportion of elderly people, as osteoporosis has become a serious challenge to the Chinese government, society, and family. Apart from the fact that all osteoporotic fractures can increase the patient’s morbidity, they can also result in fractures of the hip and vertebrae, which are associated with a significantly higher mortality. The cost of osteoporotic fractures, moreover, is a heavy burden on families, society, and even the country, which is likely to increase in the future due, in part, to the improvement in average life expectancy. Therefore, understanding the epidemiology of osteoporosis is essential and is significant for developing strategies to help reduce this problem. In this review, we will summarize the epidemiology of osteoporosis in the People’s Republic of China, including the epidemiology of osteoporotic fractures, focusing on preventive methods and the management of osteoporosis, which consist of basic measures and pharmacological treatments.