Microbial etiological agents of destructive periodontal diseases.
Microbial etiological agents of destructive periodontal diseases.
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DOI：
10.1111/j.1600-0757.1994.tb00020.x
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发表时间：
1994-06-01
影响因子：
18.6
通讯作者：
Socransky, S S
中科院分区：
文献类型：
--
作者：
Haffajee, A D;Socransky, S S
1989年，我们有机会在北卡罗来纳州查佩尔山举行的风险评估会议上发表了一篇题为“破坏性牙周病的微生物风险因素”的论文（370）。本章的部分内容就是基于这一介绍。然而，由于在过去的4年里发表了大量令人惊讶的新信息，本章将在数据和观点方面进行相当大的扩展。破坏性牙周病可能被认为是一系列影响口腔内单个或多个牙周部位的感染。这些感染具有许多特性，使得它们难以研究（如下所述），其中最重要的是，爆发可能是由一系列不同的微生物物种引起的，并且以不规则的时间间隔在各个受影响的地方发生。本章1）总结了在寻找破坏性牙周病的病原体时遇到的一些困难，2）指出了目前怀疑的牙周病原体，3）检查了与特定细菌物种存在相关的牙周附着丧失的风险，4）检查可能影响疾病进展的宿主寄生虫生态的要素，以及5）表明微生物诊断测试可能与牙周治疗的选择相结合。
In 1989, we had the opportunity to present a paper entitled “Microbial risk factors for destructive periodontal diseases”(370) at a conference on risk assessment held at Chapel Hill, North Carolina. This chapter is based in part on that presentation. However, since a surprisingly large amount of new information has been published in the last 4 years, the chapter will be considerably extended both in terms of data and viewpoint.Destructive periodontal diseases may be thought of as a series of infections that affect individual or multiple periodontal sites within the oral cavity. These infections have a number of properties that make them difficult to study (as discussed below), not the least of which is the fact that flare-ups may be caused by a series of different microbial species and take place at various affected local sites at irregular time intervals. This chapter 1) summarizes some of the difficulties encountered in seeking etiological agents of destructive periodontal diseases, 2) indicates the currently suspected periodontal pathogens, 3) examines the risk of periodontal attachment loss associated with the presence of specific bacterial species, 4) examines the elements of the host parasite ecology that may affect disease progression and 5) suggests a possible coupling of microbial diagnostic tests with the selection of periodontal therapy.