A telemetry system to chronically record muscle activity in middle-sized animals

A telemetry system to chronically record muscle activity in middle-sized animals
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DOI:
10.1016/s0165-0270(01)00528-3
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发表时间:
2002-03-15
影响因子:
3
通讯作者:
van Eijden, TMGJ
van Eijden, TMGJ
中科院分区:
医学4区
文献类型:
--
作者:
Langenbach, GEJ;van Ruijven, LJ;van Eijden, TMGJ

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无线电遥测技术可以长期记录生物电势,这些生物电势可以在自由活动的动物中获得,而不受实验者干扰。本研究的目的是测试完全植入式设备的:(1)传输范围; (2) 传输信号的特性; (3)其在长期体内肌电记录中的实际应用。通过改变设备相对于接收器的位置来测试传输范围。滤波特性的计算机模拟提供了原始信号和传输信号的比较。将设备植入咀嚼肌,然后分析遥测信号并确定活动水平,以便检查日常肌肉使用情况。该植入物的传输范围覆盖了中型动物的笼子大小,并且信号丢失最少。传输信号的特点是超过 50 Hz 的频率(部分)丢失、幅度降低以及相对于原始波形的时序略有延迟。对传输的肌电图的分析表明,该设备可用于长时间的体内肌电图记录、峰值活动水平的检测以及通过不同活动水平所花费的时间来检查一般肌肉的使用情况。 (C) 2002 Elsevier Science B.V. 保留所有权利。
Radio-telemetry enables the long-term recordings of biopotentials that may be obtained in freely moving animals without interference by the experimenter. The purpose of this study was to test a fully implantable device for: (1) its transmission range; (2) the characteristics of the transmitted signals; and (3) its actual application in long-term in vivo registration of EMG. Transmission range was tested by changing the device's position relative to the receiver. Computer simulation of the filtering characteristics provided comparison of original and transmitted signals. Implantation of the device in masticatory muscles, followed by analysis of telemetred signals and determination of activity levels allowed for examination of daily muscle use. The implant's transmission range covered the cage size for middle-sized animals with a minimum of signal dropouts. Transmitted signals were marked by (partial) loss of frequencies beyond 50 Hz, decreased amplitude and slightly delayed timing relative to original waveforms. Analysis of the transmitted EMG revealed that the device can be used for prolonged in vivo EMG registration, detection of peak activity levels, and the examination of general muscle use by the time spent at different levels of activity. (C) 2002 Elsevier Science B.V. All rights reserved.