Impact of bilateral pallidal stimulation on DYT1-generalized dystonia in Japanese patients

Impact of bilateral pallidal stimulation on DYT1-generalized dystonia in Japanese patients
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DOI:
10.1002/mds.21021
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发表时间:
2006-01-01
期刊:
影响因子:
8.6
通讯作者:
Kaji, Ryuji
Kaji, Ryuji
中科院分区:
医学1区
文献类型:
--
作者:
Goto, Satoshi;Yamada, Kazumichi;Kaji, Ryuji

文献摘要

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DYT 1基因突变引起的早发性全身性肌张力障碍是一种对药物治疗反应不佳的多动性运动障碍。在这个视频简介中,我们表明,持续的双边刺激苍白球内产生持续和显着改善的运动症状和功能障碍的日本患者DYT 1-全身性肌张力障碍。(C)2006年,《社会运动》创刊。
Early-onset generalized dystonia attributable to a DYT1 gene mutation is a hyperkinetic movement disorder that responds poorly to pharmacotherapy. In this video brief, we show that continuous bilateral stimulation of the globus pallidus internus produced sustained and marked improvements in the motor symptoms and functional disabilities of Japanese patients with DYT1-generalized dystonia. (C) 2006 Movement Disorder Society.