The ADHD response-inhibition deficit as measured by the stop task:: Replication with DSM-IV combined type, extension, and qualification
The ADHD response-inhibition deficit as measured by the stop task:: Replication with DSM-IV combined type, extension, and qualification
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DOI：
10.1023/a:1021980002473
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发表时间：
1999-10-01
影响因子：
3.6
通讯作者：
Nigg, JT
中科院分区：
文献类型：
--
作者：
Nigg, JT
尽管反应抑制已被认为是儿童注意力缺陷多动障碍 (ADHD) 的核心要素，但文献在很大程度上依赖于使用 DSM-III-R 诊断标准、测量反应抑制的旧方法、男孩样本以及未能彻底控制共病问题的研究——无论是作为诊断还是作为亚临床变异。本研究使用年龄和性别匹配的样本复制了 ADHD 合并型（DSM-IV，美国精神病学协会，1994）的反应抑制缺陷。该研究在患有多动症的男孩中复制了大约 d = 0.6 的效应值，并观察到女孩的效应值更大，尽管性别 x 群体的相互作用并不显着。患有注意力缺陷多动症的儿童也存在反应输出问题，这可以通过可变反应来体现。从样本中排除共病行为障碍、阅读障碍、广泛性焦虑症、强迫症、重度抑郁症和创伤后应激障碍并没有改变结果。相关性表明反应抑制与注意力问题和阅读水平相关。阅读问题的共变并没有消除多动症群体效应，但反应抑制与阅读的关联显然需要进一步检查。总体而言，该研究支持反应抑制在 DSM-IV ADHD 合并型中的作用，但对共病问题和其他执行功能的特异性程度有关键限定。
Although response inhibition has been proposed as a core element of child attention-deficit hyperactivity disorder (ADHD), the literature is heavily reliant on studies using DSM-III-R diagnostic criteria, older methods of measuring response inhibition, samples of boys, and failing to control thoroughly for comorbid problems-both as diagnoses and as subclinical variation. The present study replicated a deficit in response inhibition in the ADHD combined type (DSM-IV, American Psychiatric Association, 1994) using samples matched on age and sex. The study replicated an effect size of approximately d = .6 in boys with ADHD, and observed an even larger effect size for girls, although the Sex x Group interaction was nonsignificant. Children with ADHD also had problems with response output, shown by variable responding. Excluding comorbid conduct disorder, reading disorder, generalized anxiety disorder, obsessive-compulsive disorder, major depression, and posttraumatic stress disorder from the sample did not alter the results. Correlations indicated that response inhibition was associated with both attentional problems and reading level. Covarying for reading problems did not eliminate the ADHD group effect, but the association of response inhibition with reading clearly requires further examination. Overall, the study supported the role of response inhibition in the DSM-IV ADHD combined type, but with key qualifications as to degree of specificity in reference both to comorbid problems and other executive functions.