SOAP: short oligonucleotide alignment program
SOAP: short oligonucleotide alignment program
复制标题
SOAP：短寡核苷酸比对程序
DOI：
10.1093/bioinformatics/btn025
复制
发表时间：
2008-03-01
期刊：
影响因子：
5.8
通讯作者：
Wang, Jun
中科院分区：
文献类型：
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作者：
Li, Ruiqiang;Li, Yingrui;Wang, Jun
我们开发了一个名为SOAP的程序，用于将短寡核苷酸高效地比对到参考序列上，包括有间隙和无间隙的比对。该程序旨在处理使用新一代Illumina - Solexa测序技术进行平行测序所产生的大量短序列。SOAP与众多应用兼容，包括单端或双端重测序、小RNA发现以及mRNA标签序列定位。SOAP是一个命令驱动的程序，它支持多线程并行计算，并具有用于多个查询集的批处理模块。
SUMMARY
We have developed a program SOAP for efficient gapped and ungapped alignment of short oligonucleotides onto reference sequences. The program is designed to handle the huge amounts of short reads generated by parallel sequencing using the new generation Illumina-Solexa sequencing technology. SOAP is compatible with numerous applications, including single-read or pair-end resequencing, small RNA discovery and mRNA tag sequence mapping. SOAP is a command-driven program, which supports multi-threaded parallel computing, and has a batch module for multiple query sets.
AVAILABILITY
http://soap.genomics.org.cn.