A theoretical framework for biological control of soil-borne plant pathogens: Identifying effective strategies
A theoretical framework for biological control of soil-borne plant pathogens: Identifying effective strategies
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DOI：
10.1016/j.jtbi.2011.02.023
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发表时间：
2011-06-07
影响因子：
2
通讯作者：
Gilligan, Christopher A.
中科院分区：
文献类型：
--
作者：
Cunniffe, Nik J.;Gilligan, Christopher A.
我们开发和分析了一个灵活的房室模型之间的相互作用的植物宿主，土传病原体和微生物拮抗剂，用于优化生物控制。通过提取入侵和持久性阈值的主机，病原体和生物控制剂，进行平衡分析，参数和初始条件的敏感性和数值研究，我们确定成功的生物控制的标准。我们确定了生物控制的条件，以（i）防止病原体进入系统，（ii）根除已经存在的病原体，如果这是不可能的，（iii）降低病原体的密度。控制取决于病原体的流行病学和拮抗剂如何有效地定殖特定的栖息地（即健康组织、感染组织和/或土传接种物）。完全有效的控制（即病原体的根除）和完全无效的控制之间的急剧转变可以遵循生物学上可解释的参数或病原体和生物控制剂存在的初始量的轻微变化。有效的生物防治需要拮抗剂与致病系统的仔细匹配。为了预防/根除控制，拮抗剂必须定殖易感宿主。然而，为了减少疾病的流行，栖息地的范围是不太重要的拮抗剂的膨胀效率。(C)2011爱思唯尔有限公司版权所有。
We develop and analyse a flexible compartmental model of the interaction between a plant host, a soilborne pathogen and a microbial antagonist, for use in optimising biological control. By extracting invasion and persistence thresholds of host, pathogen and biological control agent, performing an equilibrium analysis, and numerical investigation of sensitivity to parameters and initial conditions, we determine criteria for successful biological control. We identify conditions for biological control (i) to prevent a pathogen entering a system, (ii) to eradicate a pathogen that is already present and, if that is not possible, (iii) to reduce the density of the pathogen. Control depends upon the epidemiology of the pathogen and how efficiently the antagonist can colonise particular habitats (i.e. healthy tissue, infected tissue and/or soil-borne inoculum). A sharp transition between totally effective control (i.e. eradication of the pathogen) and totally ineffective control can follow slight changes in biologically interpretable parameters or to the initial amounts of pathogen and biological control agent present. Effective biological control requires careful matching of antagonists to pathosystems. For preventative/eradicative control, antagonists must colonise susceptible hosts. However, for reduction in disease prevalence, the range of habitat is less important than the antagonist's bulking-up efficiency. (C) 2011 Elsevier Ltd. All rights reserved.