A DROSOPHILA MALE ACCESSORY-GLAND PROTEIN THAT IS A MEMBER OF THE SERPIN SUPERFAMILY OF PROTEINASE-INHIBITORS IS TRANSFERRED TO FEMALES DURING MATING
A DROSOPHILA MALE ACCESSORY-GLAND PROTEIN THAT IS A MEMBER OF THE SERPIN SUPERFAMILY OF PROTEINASE-INHIBITORS IS TRANSFERRED TO FEMALES DURING MATING
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DOI：
10.1016/0965-1748(94)00055-m
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发表时间：
1995-02-01
影响因子：
3.8
通讯作者：
KRAUS, K
中科院分区：
文献类型：
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作者：
COLEMAN, S;DRAHN, B;KRAUS, K
辅助腺肽 76A (Acp76A) 属于丝氨酸蛋白酶抑制剂蛋白超家族（丝氨酸蛋白酶抑制剂）。 Acp76A 是一种仅在果蝇成年雄性副腺中合成的分泌蛋白。羽化后 1 天，首先用多克隆抗体检测到雄性体内蛋白质的积累。处女雄性体内的蛋白质水平在羽化后 5-8 天达到峰值，并在至少 20 天内保持稳定。交配后，雄性体内 Acp76A 的数量急剧下降，但在交配后 24 小时恢复。交配后，Acp76A 立即出现在雌性子宫中。交配后 6 小时，雌性体内检测到的 Acp76A 数量急剧减少。
Accessory gland peptide 76A, (Acp76A), belongs to the serpin superfamily of proteins (serine protease inhibitors). Acp76A is a secreted protein synthesized only in the Drosophila melanogaster adult male accessory gland. Accumulation of the protein in males is first detected with polyclonal antibodies at 1 day after eclosion. The level of the protein in virgin males reaches a peak 5-8 days post-eclosion, and remains constant for at least 20 days. Upon mating the amount of Acp76A in males drops dramatically, but recovers by 24 h after mating. Immediately after mating the Acp76A is found in the female uterus. By 6 h after mating the amount of Acp76A detected in females is drastically reduced.