Long-Term Effects of Coordinative Training in Degenerative Cerebellar Disease
Long-Term Effects of Coordinative Training in Degenerative Cerebellar Disease
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DOI：
10.1002/mds.23222
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发表时间：
2010-10-15
影响因子：
8.6
通讯作者：
Synofzik, Matthis
中科院分区：
文献类型：
--
作者：
Ilg, Winfried;Broetz, Doris;Synofzik, Matthis
很少有临床研究评价退行性小脑疾病患者的理疗干预。特别是，长期影响和转移到日常生活活动的证据很少。我们最近已经证明，协调训练导致运动表现的短期改善。为了评估长期受益和转化为真实的世界功能，我们在此评估了4周强化协调训练后1年的运动表现和日常生活活动的成就，随后进行了家庭训练计划。通过临床评定量表、目标达成评分和定量运动分析评估效果。尽管1年后由于疾病进展，运动表现逐渐下降，共济失调症状逐渐增加，但运动表现和日常生活活动的改善持续存在。因此，对于患有退行性小脑疾病的患者，持续的协调训练也会导致长期的改善，这会转化为真实的世界功能。(C)2010年运动障碍协会
Few clinical studies have evaluated physiotherapeutic interventions for patients with degenerative cerebellar disease. In particular, evidence for long-term effects and transfer to activities of daily life is rare. We have recently shown that coordinative training leads to short-term improvements in motor performance. To evaluate long-term benefits and translation to real world function, we here assessed motor performance and achievements in activities of daily life 1 year after a 4 week intensive coordinative training, which was followed by a home training program. Effects were assessed by clinical rating scales, a goal attainment score and quantitative movement analysis. Despite gradual decline of motor performance and gradual increase of ataxia symptoms due to progression of disease after 1 year, improvements in motor performance and achievements in activities of daily life persisted. Thus, also in patients with degenerative cerebellar disease, continuous coordinative training leads to long-term improvements, which translate to real world function. (C) 2010 Movement Disorder Society