MAGNETIC STIMULATION OF THE HUMAN-BRAIN - FACILITATION OF MOTOR-RESPONSES BY VOLUNTARY CONTRACTION OF IPSILATERAL AND CONTRALATERAL MUSCLES WITH ADDITIONAL OBSERVATIONS ON AN AMPUTEE

MAGNETIC STIMULATION OF THE HUMAN-BRAIN - FACILITATION OF MOTOR-RESPONSES BY VOLUNTARY CONTRACTION OF IPSILATERAL AND CONTRALATERAL MUSCLES WITH ADDITIONAL OBSERVATIONS ON AN AMPUTEE
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DOI:
10.1016/0304-3940(86)90565-3
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发表时间:
1986-11-11
影响因子:
2.5
通讯作者:
MURRAY, NMF
MURRAY, NMF
中科院分区:
医学4区
文献类型:
--
作者:
HESS, CW;MILLS, KR;MURRAY, NMF

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在头皮上的线圈中产生的强烈快速变化的磁场可以激发手部肌肉的运动路径。在阈上刺激下,小指展肌的肌肉动作电位的幅度增加;肌肉本身的弱收缩,同侧第一骨间背侧肌的弱收缩,对侧小指展肌的较强收缩,但不是对侧第一骨间背侧肌的收缩,也不是同侧股四头肌的收缩。这种对大脑刺激的反应的促进可能通过两种机制发生,一种与将注意力集中到特定的手上有关,第二种涉及同源运动通路的兴奋性的上升。
An intense rapidly changing magnetic field generated in a coil over the scalp can excite motor pathways to hand muscles. With a suprathreshold stimulus, the amplitude of the muscle action potential of the abductor digiti minimi is increased; by weak contraction of the muscle itself, by weak contraction of the ipsilateral first dorsal interosseous, by stronger contraction of the contralateral abductor digiti minimi, but not by contraction of the contralateral first dorsal interosseous, nor by the ipsilateral quadriceps muscle. This facilitation of response to brain stimulation may occur by two mechanisms, one related to the focussing of attention onto particular hand, the second involving a rise in excitability of homologous motor pathways.