Comparative outcomes of femtosecond laser-assisted cataract surgery and manual phacoemusification: a six-month follow-up
Comparative outcomes of femtosecond laser-assisted cataract surgery and manual phacoemusification: a six-month follow-up
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DOI：
10.1111/ceo.12695
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发表时间：
2016-08-01
影响因子：
4
通讯作者：
Yao, Ke
中科院分区：
文献类型：
--
作者：
Yu, Yinhui;Chen, Xinyi;Yao, Ke
背景旨在探讨接受飞秒激光辅助白内障手术（FLACS）与手动超声乳化白内障手术（PCS）的疗效和安全性结果。设计前瞻性连续非随机比较队列研究。参与者共有来自106名患者的124只眼睛（FLACS中70只，PCS中54只）。方法FLACS与PCS超过6个月的比较。主要结果测量黄斑中心子视野厚度(CST)、立方体体积(CV)、立方体平均厚度(CAT)、内皮细胞密度(ECD)、中央角膜厚度(CCT)和光子计数值(PCV)。结果术后CST、CV和CAT增加，6个月仍未恢复至术前水平。在整个随访过程中，各组之间的值相似，并且与基线的变化比较也没有显示显着差异。术前ECD差异有显着性，术后下降，随访期间保持稳定，1个月时最低。 FLACS 比 PCS 具有更多的内皮细胞损失，但并不显着。两组的 CCT 均有所增加，在第一天达到最大值，此后趋于下降。术后数值和平均增加没有发现显着差异。在两组中，平均 PCV 从术前到第一天、第一周和第一个月均有所增加。 FLACS 中的耀斑值低于 PCS，在 6 个月时达到统计学显着性（P=0.001）。然而，每次就诊时 PCV 变化的差异均无显着差异。 结论 FLACS 和 PCS 在进行白内障手术时取得了相似的安全性和有效性结果。术后 6 个月时，FLACS 眼的耀斑值低于 PCS 眼。
BackgroundTo explore efficacy and safety outcomes in patients undergoing femtosecond laser-assisted cataract surgery (FLACS) versus manual phacoemulsification cataract surgery (PCS).DesignProspective consecutive nonrandomized comparative cohort study.ParticipantsA total of 124 eyes from 106 patients (70 in FLACS and 54 in PCS).MethodsComparison of FLACS with PCS over 6months.Main Outcome MeasuresMacular central subfield thickness (CST), cube volume (CV), cube average thickness (CAT), endothelial cell density (ECD), central corneal thickness (CCT) and photon count value (PCV).ResultsCST, CV and CAT increased postoperatively, which did not return to preoperative levels by 6months. The values were similar between groups throughout the follow-up, and comparison of changes from baseline also showed no significant difference. Preoperative ECD showed significant difference, which decreased postoperatively and remained stable during follow-up, being lowest at 1month. FLACS had greater endothelial cell loss than PCS, which was not significant. CCT in both groups increased, reaching maximum on day one and tended to decrease thereafter. No significant differences were found regarding postoperative values and the mean increase. In both groups, mean PCV increased from preoperatively to day one, week one and month one. Flare values in FLACS were lower than PCS, reaching statistical significance at 6months (P=0.001). However, the differences in changes of PCV were not significantly different at any visit.ConclusionsBoth FLACS and PCS achieved similar safety and efficacy outcomes for performing cataract surgery. Flare values in eyes with FLACS were lower than those with PCS at 6months postoperatively.