Article Midbrain Dopamine Neurons Signal Preference for Advance Information about Upcoming Rewards
Article Midbrain Dopamine Neurons Signal Preference for Advance Information about Upcoming Rewards
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通讯作者：
Ethan S. Bromberg-Martin;O. Hikosaka
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作者：
Ethan S. Bromberg-Martin;O. Hikosaka
总结一下，对未来的渴望是日常生活中一种强大的动力，但目前还不清楚这种渴望是如何由大脑中的神经元产生的。在这里，我们展示了当猕猴被提供不同级别的水奖励时，它们会寻求关于其大小的预先信息。此外，发出预期水量信号的中脑多巴胺神经元也发出信息期望的信号，其方式与动物偏好的强度相关。我们的数据显示，单个多巴胺神经元同时处理原始和认知奖赏，并建议必须修改当前的奖赏寻求理论，将信息寻求包括在内。
SUMMARY The desire to know what the future holds is a powerful motivator in everyday life, but it is unknown how this desire is created by neurons in the brain. Here we show that when macaque monkeys are offered a water reward of variable magnitude, they seek advance information about its size. Furthermore, the same midbrain dopamine neurons that signal the expected amount of water also signal the expectation of information, in a manner that is correlated with the strength of the animal's preference. Our data show that single dopamine neurons process both primitive and cognitive rewards, and suggest that current theories of reward-seeking must be revised to include information-seeking.