On the Alert for Cytokine Storm: Immunopathology in COVID-19
On the Alert for Cytokine Storm: Immunopathology in COVID-19
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DOI：
10.1002/art.41285
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发表时间：
2020-05-10
影响因子：
13.3
通讯作者：
Nigrovic, Peter A.
中科院分区：
文献类型：
--
作者：
Henderson, Lauren A.;Canna, Scott W.;Nigrovic, Peter A.
COVID-19的不良预后与细胞因子风暴综合征的临床和实验室特征相关。广泛筛选细胞因子风暴和早期靶向抗炎治疗可能预防免疫病理，并有助于节省有限的卫生保健资源。虽然研究仍在进行中，但从细胞因子风暴综合征的临床经验中推断出来的结果可能有利于照顾严重COVID-19患者的多学科团队。
Poor outcomes in COVID-19 correlate with clinical and laboratory features of cytokine storm syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy may prevent immunopathology and could help conserve limited health care resources. While studies are ongoing, extrapolating from clinical experience in cytokine storm syndromes may benefit the multidisciplinary teams caring for patients with severe COVID-19.