The opposite effects of central and peripheral vasoactive intestinal polypeptide on blood pressure in rats
The opposite effects of central and peripheral vasoactive intestinal polypeptide on blood pressure in rats
复制标题
中枢和外周血管活性肠多肽对大鼠血压的相反作用
DOI：
10.1016/0304-3940(83)90035-6
复制
发表时间：
1983
影响因子：
2.5
通讯作者：
M. Phillips
中科院分区：
文献类型：
--
作者：
R. Castro;M. Phillips
In conscious normotensive rats catheterized for continuous recording of blood pressure, intracerebroventricular injections of vasoactive intestinal polypeptide (VIP) produced pressor responses in contrast to depressor effects when given intravenously. The pressor effect was not mediated by angiotensin II since pretreatment with an angiotensin antagonist failed to block the response. These findings show that there are separate mechanisms for central versus peripheral effects of VIP.
