Paleo-Eskimo mtDNA genome reveals matrilineal discontinuity in Greenland
Paleo-Eskimo mtDNA genome reveals matrilineal discontinuity in Greenland
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DOI：
10.1126/science.1159750
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发表时间：
2008-06-27
期刊：
影响因子：
56.9
通讯作者：
Willerslev, Eske
中科院分区：
文献类型：
--
作者：
Gilbert, M. Thomas P.;Kivisild, Toomas;Willerslev, Eske
加拿大北部和格陵兰岛的考古遗迹记录了古爱斯基摩人的Saqqaq和Independence I文化，它们代表了人类向新世界北部极端地区最早的扩张。然而，他们的起源和与后来文化的遗传关系是未知的。我们对一个古爱斯基摩人的线粒体基因组进行了测序，方法是使用从格陵兰岛早期萨卡克人定居点出土的3400至4500年前的冷冻头发。该样本与现代美洲原住民和新爱斯基摩人不同，属于单倍群D2a1，该群先前在现代阿留申人和西伯利亚的Sireniki Yuit人中观察到。这一结果表明，最早进入新世界北部极端地区的移民来自白令海地区的人口，与美洲原住民或后来取代他们的新爱斯基摩人没有直接关系。
The Paleo- Eskimo Saqqaq and Independence I cultures, documented from archaeological remains in Northern Canada and Greenland, represent the earliest human expansion into the New World's northern extremes. However, their origin and genetic relationship to later cultures are unknown. We sequenced a mitochondrial genome from a Paleo- Eskimo human by using 3400- to 4500- year- old frozen hair excavated from an early Greenlandic Saqqaq settlement. The sample is distinct from modern Native Americans and Neo- Eskimos, falling within haplogroup D2a1, a group previously observed among modern Aleuts and Siberian Sireniki Yuit. This result suggests that the earliest migrants into the New World's northern extremes derived from populations in the Bering Sea area and were not directly related to Native Americans or the later Neo- Eskimos that replaced them.