Smoking promotes peritonsillar abscess
Smoking promotes peritonsillar abscess
复制标题
DOI：
10.1007/s00405-013-2474-4
复制
发表时间：
2013-11-01
影响因子：
2.6
通讯作者：
Ovesen, Therese
中科院分区：
文献类型：
--
作者：
Klug, Tejs Ehlers;Rusan, Maria;Ovesen, Therese
扁桃体周围脓肿（PTA）是急性扁桃体炎的常见并发症，特别是在青少年和年轻人中。吸烟最常见于青春期和成年初期。该研究探讨了吸烟是否会增加 PTA 的风险，以及吸烟是否与 PTA 中的细菌发现有关。 2001 年 1 月至 2006 年 12 月期间入住奥尔胡斯大学医院耳鼻喉科的所有 PTA 患者均纳入本研究。获得了丹麦人口吸烟习惯的年龄和性别分层数据以及奥尔胡斯县同一 6 年的人口数据。 847 名 PTA 患者中，有 679 名 (80%) 的吸烟状况可用。 247 名 (36%) 患者承认每天吸烟。吸烟者与非吸烟者发生 PTA 的年龄分层优势比在 1.9-4.7 范围内。坏死梭杆菌和β-溶血性链球菌在吸烟者和非吸烟者之间分布均匀。与女性相比，男性 PTA 发生率较高的 29% 可以归因于男性吸烟率较高。校正不同性别吸烟率的差异后，计算得出男性患 PTA 的风险比女性高 9.5%。在所有年龄段的男性和女性中，吸烟均与 PTA 风险显着增加相关。没有发现患有 PTA 的吸烟者和非吸烟者的微生物菌群存在差异。
Peritonsillar abscess (PTA) is a frequent complication to acute tonsillitis, in particular in adolescents and young adults. Smoking is most commonly initiated during adolescence and young adulthood. The study examines whether smoking increases the risk of PTA and whether smoking is associated with the bacterial findings in PTA. All patients with PTA admitted to the Ear-Nose-Throat Department at Aarhus University Hospital from January 2001 through December 2006 were included in the study. Age- and gender-stratified data on smoking habits in the Danish population and demographic data for Aarhus County for the same 6 years were obtained. Smoking status was available for 679 (80 %) of 847 patients with PTA. 247 (36 %) patients admitted to daily tobacco smoking. Age-stratified odds ratios of smokers compared to non-smokers, for developing PTA, were in the range of 1.9-4.7. Fusobacterium necrophorum and beta-hemolytic streptococci were equally distributed between smokers and non-smokers. Twenty nine percent of the higher incidence of PTA among males compared to females could be explained by a higher prevalence of smoking in males. After correcting for differences in smoking prevalence by gender, the risk of PTA was calculated to be 9.5 % higher among males than females. Smoking was associated with significantly increased risk of PTA in both males and females of all ages. No differences in the microbiological flora of smokers and non-smokers with PTA were found.