Low-Dose 3D Time-Resolved Magnetic Resonance Angiography (MRA) of the Supraaortic Arteries: Correlation With High Spatial Resolution 3D Contrast-Enhanced MRA
Low-Dose 3D Time-Resolved Magnetic Resonance Angiography (MRA) of the Supraaortic Arteries: Correlation With High Spatial Resolution 3D Contrast-Enhanced MRA
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DOI：
10.1002/jmri.22396
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发表时间：
2011-01-01
影响因子：
4.4
通讯作者：
Kim, Bum-Soo
中科院分区：
文献类型：
--
作者：
Lee, Youn-Joo;Laub, Gerhard;Kim, Bum-Soo
目的：评价低剂量、3D时间分辨对比增强磁共振血管造影（TR-CEMRA）评估主动脉上血管的可行性，并与高分辨率对比增强MRA（HR-CEMRA）的结果进行比较。材料和方法：这是一项机构审查委员会批准的回顾性研究。45名连续患者在3.0 T下接受了对比增强3D TR-CEMRA和3D HR-CEMRA，以评价神经血管疾病。对于TR-CEMRA，以1 mL的恒定剂量给予钆布醇（与患者体重无关），对于HR-CEMRA，以0.1 mmol/kg的恒定剂量给予钆布醇。两名读者评价图像质量使用四点量表（从0 =优秀到3 =非诊断），并随后将每个狭窄分为临床相关类别：正常（0%），轻度狭窄（50%），occlusion.Results：低剂量TR-CEMRA的整体图像质量是在诊断范围（中位数0，范围03）。关于狭窄的分级。TWIST序列TR-CEMRA与HR-CEMRA相关（r = 0.668，P < 0.001）。就TR-CEMRA与HR-CEMRA的比较而言，在评价狭窄或闭塞的675个主动脉上动脉节段中，611个节段的结果一致（90.5%），高估41/675（6.1%），低估23 675（3.4%）。通过给予小剂量造影剂（1 cc）实现TR-CEMRA在主动脉上的评价中产生快速和重要的功能和解剖信息。由于空间分辨率有限，与HR-CEMRA相比，TR-CEMRA在当前参数下倾向于高估较小颅内动脉的狭窄。
Purpose: To evaluate the feasibility of low-dose, 3D time-resolved contrast-enhanced magnetic resonance angiography (TR-CEMRA) in the assessment of the supraaortic vessel, and to compare the results with high-resolution contrast-enhanced MRA (HR-CEMRA).Materials and Methods: This was an Institutional Review Board-approved retrospective study. Forty-five consecutive patients underwent contrast-enhanced 3D TR-CEMRA and 3D HR-CEMRA for evaluation of neurovascular disease at 3.0 T. Gadobutrol was administered at a constant dose of 1 mL for TR-CEMRA (independent of patient weight), and 0.1 mmol/kg for HR-CEMRA. Two readers evaluated image quality using a four-point scale (from 0 = excellent to 3 = nondiagnostic), and subsequently graded each stenosis into clinically relevant categories: normal (0%), mild stenosis (50%), and occlusion.Results: The overall image quality for low-dose TR-CEMRA was in the diagnostic range (median 0, range 03). On the grading of stenosis. TR-CEMRA using the TWIST sequence correlated with HR-CEMRA (r = 0.668, P < 0.001). In terms of the comparison of TR-CEMRA with HR-CEMRA, of the 675 supraaortic arterial segments evaluated for stenosis or occlusion, agreement occurred in 611 of 675 (90.5%), overestimation in 41 of 675 (6.1%), and underestimation 23 of 675 (3.4%).Conclusion: TR-CEMRA achieved by administration of a small contrast dose (1 cc) yields rapid and important functional and anatomical information in the evaluation of supraaortic arteries. Due to limited spatial resolution, TR-CEMRA at the current parameters has a tendency to overestimate the stenosis of smaller intracranial arteries compared to HR-CEMRA.