Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort
Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort
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DOI：
10.1371/journal.pone.0183732
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发表时间：
2017-09-05
期刊：
影响因子：
3.7
通讯作者：
Lambiase, Pier D.
中科院分区：
文献类型：
--
作者：
Orini, Michele;Tinker, Andrew;Lambiase, Pier D.
背景运动心率（HR）反应提供了有关自主神经功能的有用信息并具有预后价值，但其在很长一段时间内的再现性（将其用作临床生物标志物的关键要求）尚未确定。目的确定次最大运动和一分钟恢复期间心率动态的个体内再现性。方法来自英国生物银行心脏体能评估测试的1187名个体重复标准运动压力测试两次（回想一下）时间 34.2 +/- 2.8 个月）并进行了前瞻性研究。结果 821 人符合可重复性分析的纳入标准，包括评估之间的峰值工作量差异
BackgroundThe heart rate (HR) response to exercise provides useful information about the autonomic function and has prognostic value, but its reproducibility over a long period of time, a critical requirement for using it as a clinical biomarker, is undetermined.AimTo determine the intra-individual reproducibility of HR dynamics during sub-maximum exercise and one minute recovery.Methods1187 individuals from the Cardio physical fitness assessment test of the UK Biobank repeated a standard exercise stress test twice (recall time 34.2 +/- 2.8 months) and were prospectively studied.Results821 individuals complied with inclusion criteria for reproducibility analysis, including peak workload differences between assessments